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Found 1 matching record:

Displaying record number 54628

HXB2 Location  Gag(126-143)   Gag Epitope Map
View variants at this location
Epitope SQVSQNYPIVQNLQGQMV   Epitope Alignment
Variants
-kVSQNYPIVQNLQGQMV   subtype-specific susceptible form
Epitope Name GAG-18
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  2269
Epitope Seq.  SQVSQNYPIVQNLQGQMV
Variant Seq.  -kVSQNYPIVQNLQGQMV
Mutations S/- Q/K
Epitope Location S1- Q2K
HXB2 Location S126- Q127K
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (11.1%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


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