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Found 1 matching record:

Displaying record number 54625

HXB2 Location  Gag(162-172)   Gag Epitope Map
View variants at this location
Epitope KAFSPEVIPMF   Epitope Alignment
Variants
KgFnPEVIPMF   observed variant
KnFSPEVIPMF   observed variant
KsFSPEVIPMF   observed variant
KgFSPEVIPMF   observed variant
KgFkPEVIPMF   observed variant
KsFSPEtIPMF   observed variant
Epitope Name KF11
Species (MHC/HLA human(B*57:01, B*57:03)

Variant Details

Showing all: 6 variant(s).


Variant ID.  219
Epitope Seq.  KAFSPEVIPMF
Variant Seq.  KgFnPEVIPMF
Mutations A/G S/N
Epitope Location A2G S4N
HXB2 Location A163G S165N
Mutation Type OV: observed variant
Epitope Subtype C
Note Epitope highly variant in African cohort when restricted by B*5703 but highly conserved in B*5701 European cohort.


Variant ID.  220
Epitope Seq.  KAFSPEVIPMF
Variant Seq.  KnFSPEVIPMF
Mutations A/N
Epitope Location A2N
HXB2 Location A163N
Mutation Type OV: observed variant
Epitope Subtype C
Note Epitope highly variant in African cohort when restricted by B*5703 but highly conserved in B*5701 European cohort.


Variant ID.  221
Epitope Seq.  KAFSPEVIPMF
Variant Seq.  KsFSPEVIPMF
Mutations A/S
Epitope Location A2S
HXB2 Location A163S
Mutation Type OV: observed variant
Epitope Subtype C
Note Epitope highly variant in African cohort when restricted by B*5703 but highly conserved in B*5701 European cohort.


Variant ID.  222
Epitope Seq.  KAFSPEVIPMF
Variant Seq.  KgFSPEVIPMF
Mutations A/G
Epitope Location A2G
HXB2 Location A163G
Mutation Type OV: observed variant
Epitope Subtype C
Note Epitope highly variant in African cohort when restricted by B*5703 but highly conserved in B*5701 European cohort.


Variant ID.  223
Epitope Seq.  KAFSPEVIPMF
Variant Seq.  KgFkPEVIPMF
Mutations A/G S/K
Epitope Location A2G S4K
HXB2 Location A163G S165K
Mutation Type OV: observed variant
Epitope Subtype C
Note Epitope highly variant in African cohort when restricted by B*5703 but highly conserved in B*5701 European cohort.


Variant ID.  224
Epitope Seq.  KAFSPEVIPMF
Variant Seq.  KsFSPEtIPMF
Mutations A/S V/T
Epitope Location A2S V7T
HXB2 Location A163S V168T
Mutation Type OV: observed variant
Epitope Subtype C
Note Epitope highly variant in African cohort when restricted by B*5703 but highly conserved in B*5701 European cohort.

References

Frater2007 A. J. Frater, H. Brown, A. Oxenius, H. F. Günthard, B. Hirschel, N. Robinson, A. J. Leslie, R. Payne, H. Crawford, A. Prendergast, C. Brander, P. Kiepiela, B. D. Walker, P. J. R. Goulder, A. McLean, and R. E. Phillips. Effective T-Cell Responses Select Human Immunodeficiency Virus Mutants and Slow Disease Progression. J. Virol., 81(12):6742-6751, Jun 2007. PubMed ID: 17409157. Show all entries for this paper.


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