HIV molecular immunology database
Found 1 matching record:
|HXB2 Location||Gag(28-36)|| Gag Epitope Map
View variants at this location
Showing all: 1 variant(s).
|Mutation Type||E: escape documented in this paper
LE: literature escape
|Method||CD8 T-cell Elispot - IFNy, Sequence|
|Note||This variant from the HXB2 sequence was present in the restricting HLA-A24 allele carrying mother, M-1003, as well as her HLA-A24-carrying infant, P-1189. Decreased recognition of the variant was seen relative to wild type index epitope. This variant was still detected at 12 months of age in infant P-1189. While the mother could recognize index epitope QW9, but not this variant, infant P-1189 could not recognize either index or variant.|
Sanchez-Merino2005 Victor Sanchez-Merino, Siwei Nie, and Katherine Luzuriaga. HIV-1-Specific CD8+ T Cell Responses and Viral Evolution in Women and Infants. J. Immunol., 175(10):6976-6986, 15 Nov 2005. PubMed ID: 16272358. Show all entries for this paper.