HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(24-31) | Gag Epitope Map
View variants at this location |
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| Epitope |
GGKKKYKL
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Epitope Alignment | ||||
| Variants |
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| Epitope Name | GL8 | |||||
| Species (MHC/HLA) | human(B*08) | |||||
Showing all: 1 variant(s).
| Variant ID. | 1573 |
|---|---|
| Epitope Seq. | GGKKKYKL |
| Variant Seq. | GGrKKYKL |
| Mutations | K/R |
| Epitope Location | K3R |
| HXB2 Location | K26R |
| Mutation Type | R: reversion |
| Method | CD8 T-cell Elispot - IFNy, Sequence |
| Note | This variant from the HXB2 sequence was present in the restricting HLA-B8 allele carrying mother, M-1001, as well as her non-HLA-B8-carrying infant, P-1024. Infant P-1024 had lost this variant by 15 months of age. |
Sanchez-Merino2005 Victor Sanchez-Merino, Siwei Nie, and Katherine Luzuriaga. HIV-1-Specific CD8+ T Cell Responses and Viral Evolution in Women and Infants. J. Immunol., 175(10):6976-6986, 15 Nov 2005. PubMed ID: 16272358. Show all entries for this paper.