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Found 1 matching record:

Displaying record number 53840

HXB2 Location  Gag(24-31)   Gag Epitope Map
View variants at this location
Epitope GGKKKYKL   Epitope Alignment
Variants
GGrKKYKL   reversion
Epitope Name GL8
Species (MHC/HLA human(B*08)

Variant Details

Showing all: 1 variant(s).


Variant ID.  1573
Epitope Seq.  GGKKKYKL
Variant Seq.  GGrKKYKL
Mutations K/R
Epitope Location K3R
HXB2 Location K26R
Mutation Type R: reversion
Method CD8 T-cell Elispot - IFNy, Sequence
Note This variant from the HXB2 sequence was present in the restricting HLA-B8 allele carrying mother, M-1001, as well as her non-HLA-B8-carrying infant, P-1024. Infant P-1024 had lost this variant by 15 months of age.

References

Sanchez-Merino2005 Victor Sanchez-Merino, Siwei Nie, and Katherine Luzuriaga. HIV-1-Specific CD8+ T Cell Responses and Viral Evolution in Women and Infants. J. Immunol., 175(10):6976-6986, 15 Nov 2005. PubMed ID: 16272358. Show all entries for this paper.


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