HIV molecular immunology database
Found 1 matching record:
|HXB2 Location||Gag(71-79)|| Gag Epitope Map
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Showing all: 1 variant(s).
|Epitope Location||L5I R6K|
|HXB2 Location||L75I R76K|
|Mutation Type||DHB: diminished HLA binding or increased off-rate
E: escape documented in this paper
|Method||CD8 T-cell Elispot - IFNy, HLA binding, Sequence|
|Note||This variant was seen in Donor2 and Recipient2, both of whom carried the restricting HLA-A*0101 allele. It was not recognized and binding to HLA was reduced.|
Milicic2005 Anita Milicic, Charles T. T. Edwards, Stéphane Hué, Julie Fox, Helen Brown, Tilly Pillay, Jan W. Drijfhout, Jonathan N. Weber, Edward C. Holmes, Sarah J. Fidler, Hua-Tang Zhang, and Rodney E. Phillips. Sexual Transmission of Single Human Immunodeficiency Virus Type 1 Virions Encoding Highly Polymorphic Multisite Cytotoxic T-Lymphocyte Escape Variants. J. Virol., 79(22):13953-13962, Nov 2005. PubMed ID: 16254331. Show all entries for this paper.