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Displaying record number 53755

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
Variants
SLfNTiATL   escape documented in this paper
SLfNTiAaL   observed variant
SLfNTVAvL   escape documented in this paper
SLfsTVAvL   observed variant
SLfNTVAvp   observed variant
SLfNTiAvL   observed variant
Epitope Name SL9
Species (MHC/HLA human(A2)

Variant Details

Showing all: 6 variant(s).


Variant ID.  753
Epitope Seq.  SLYNTVATL
Variant Seq.  SLfNTiATL
Mutations Y/F V/I
Epitope Location Y3F V6I
HXB2 Location Y79F V82I
Mutation Type E: escape documented in this paper
Method CD8 T-cell Elispot - IFNy, Chromium-release assay
Note Variant was found in the beginning and at the end of a 7 year period in a patient. It was not recognized by patient CTLs.


Variant ID.  754
Epitope Seq.  SLYNTVATL
Variant Seq.  SLfNTiAaL
Mutations Y/F V/I T/A
Epitope Location Y3F V6I T8A
HXB2 Location Y79F V82I T84A
Mutation Type OV: observed variant
Note Variant was found in 1/22 clones at the beginning of a 7 year period in a patient.


Variant ID.  755
Epitope Seq.  SLYNTVATL
Variant Seq.  SLfNTVAvL
Mutations Y/F T/V
Epitope Location Y3F T8V
HXB2 Location Y79F T84V
Mutation Type E: escape documented in this paper
Method CD8 T-cell Elispot - IFNy, Chromium-release assay
Note Variant dominated in the middle of a 7 year period in a patient. It was not recognized by patient CTLs.


Variant ID.  756
Epitope Seq.  SLYNTVATL
Variant Seq.  SLfsTVAvL
Mutations Y/F N/S T/V
Epitope Location Y3F N4S T8V
HXB2 Location Y79F N80S T84V
Mutation Type OV: observed variant
Note Variant was found in 1/28 clones at the middle of a 7 year period in a patient.


Variant ID.  757
Epitope Seq.  SLYNTVATL
Variant Seq.  SLfNTVAvp
Mutations Y/F T/V L/P
Epitope Location Y3F T8V L9P
HXB2 Location Y79F T84V L85P
Mutation Type OV: observed variant
Note Variant was found in 1/28 clones at the middle of a 7 year period in a patient.


Variant ID.  758
Epitope Seq.  SLYNTVATL
Variant Seq.  SLfNTiAvL
Mutations Y/F V/I T/V
Epitope Location Y3F V6I T8V
HXB2 Location Y79F V82I T84V
Mutation Type OV: observed variant
Note Variant was found at the end of a 7 year period in a patient.

References

Koibuchi2005a Tomohiko Koibuchi, Todd M. Allen, Mathias Lichterfeld, Stanley K. Mui, Kristin M. O'Sullivan, Alicja Trocha, Spyros A. Kalams, R. Paul Johnson, and Bruce D. Walker. Limited Sequence Evolution within Persistently Targeted CD8 Epitopes in Chronic Human Immunodeficiency Virus Type 1 Infection. J. Virol., 79(13):8171-8181, Jul 2005. PubMed ID: 15956562. Show all entries for this paper.


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