HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(77-85) | Gag Epitope Map
View variants at this location |
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| Epitope |
SLYNTVATL
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Epitope Alignment | |||||||||||||||||||
| Variants |
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| Epitope Name | SL9 | ||||||||||||||||||||
| Species (MHC/HLA) | human(A2) | ||||||||||||||||||||
Showing all: 6 variant(s).
| Variant ID. | 753 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLfNTiATL |
| Mutations | Y/F V/I |
| Epitope Location | Y3F V6I |
| HXB2 Location | Y79F V82I |
| Mutation Type | E: escape documented in this paper |
| Method | CD8 T-cell Elispot - IFNy, Chromium-release assay |
| Note | Variant was found in the beginning and at the end of a 7 year period in a patient. It was not recognized by patient CTLs. |
| Variant ID. | 754 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLfNTiAaL |
| Mutations | Y/F V/I T/A |
| Epitope Location | Y3F V6I T8A |
| HXB2 Location | Y79F V82I T84A |
| Mutation Type | OV: observed variant |
| Note | Variant was found in 1/22 clones at the beginning of a 7 year period in a patient. |
| Variant ID. | 755 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLfNTVAvL |
| Mutations | Y/F T/V |
| Epitope Location | Y3F T8V |
| HXB2 Location | Y79F T84V |
| Mutation Type | E: escape documented in this paper |
| Method | CD8 T-cell Elispot - IFNy, Chromium-release assay |
| Note | Variant dominated in the middle of a 7 year period in a patient. It was not recognized by patient CTLs. |
| Variant ID. | 756 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLfsTVAvL |
| Mutations | Y/F N/S T/V |
| Epitope Location | Y3F N4S T8V |
| HXB2 Location | Y79F N80S T84V |
| Mutation Type | OV: observed variant |
| Note | Variant was found in 1/28 clones at the middle of a 7 year period in a patient. |
| Variant ID. | 757 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLfNTVAvp |
| Mutations | Y/F T/V L/P |
| Epitope Location | Y3F T8V L9P |
| HXB2 Location | Y79F T84V L85P |
| Mutation Type | OV: observed variant |
| Note | Variant was found in 1/28 clones at the middle of a 7 year period in a patient. |
| Variant ID. | 758 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLfNTiAvL |
| Mutations | Y/F V/I T/V |
| Epitope Location | Y3F V6I T8V |
| HXB2 Location | Y79F V82I T84V |
| Mutation Type | OV: observed variant |
| Note | Variant was found at the end of a 7 year period in a patient. |
Koibuchi2005a Tomohiko Koibuchi, Todd M. Allen, Mathias Lichterfeld, Stanley K. Mui, Kristin M. O'Sullivan, Alicja Trocha, Spyros A. Kalams, R. Paul Johnson, and Bruce D. Walker. Limited Sequence Evolution within Persistently Targeted CD8 Epitopes in Chronic Human Immunodeficiency Virus Type 1 Infection. J. Virol., 79(13):8171-8181, Jul 2005. PubMed ID: 15956562. Show all entries for this paper.