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Displaying record number 53748

HXB2 Location Gag(20-29) Gag Epitope Map
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Epitope

RLRPGGKKKY

Epitope Alignment

Variants

RLRPGGrKKY susceptible form

Epitope Name RY10

Species (MHC/HLA) human(B62)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`752`
Epitope Seq.	`RLRPGGKKKY`
Variant Seq.	`RLRPGGrKKY`
Mutations	K/R
Epitope Location	K7R
HXB2 Location	K26R
Mutation Type	SF: susceptible form
Method	CD8 T-cell Elispot - IFNy, Chromium-release assay
Note	Variant was detected over a 5 year time period in a patient. The variant was better recognized than the wt epitope by patient CTLs.

References

Koibuchi2005a Tomohiko Koibuchi, Todd M. Allen, Mathias Lichterfeld, Stanley K. Mui, Kristin M. O'Sullivan, Alicja Trocha, Spyros A. Kalams, R. Paul Johnson, and Bruce D. Walker. Limited Sequence Evolution within Persistently Targeted CD8 Epitopes in Chronic Human Immunodeficiency Virus Type 1 Infection. J. Virol., 79(13):8171-8181, Jul 2005. PubMed ID: 15956562. Show all entries for this paper.