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Found 1 matching record:

Displaying record number 53636

HXB2 Location  Gag(147-155)   Gag Epitope Map
View variants at this location
Epitope ISPRTLNAW   Epitope Alignment
Variants
lSPRTLNAW   observed variant
Epitope Name IW9
Species (MHC/HLA human(B57)

Variant Details

Showing all: 1 variant(s).


Variant ID.  138
Epitope Seq.  ISPRTLNAW
Variant Seq.  lSPRTLNAW
Mutations I/L
Epitope Location I1L
HXB2 Location I147L
Mutation Type OV: observed variant
Method CD8 T-cell Elispot - IFNy
Note ISPRTLNAW had a variant lSPRTLNAW in 7/10 B57+ subjects, and 4/9 B57- subjects; 2 other variants were observed, but there was no apparent sequence selection in this epitope.

References

Currier2005 Jeffrey R. Currier, Matthew E. Harris, Josephine H. Cox, Francine E. McCutchan, Deborah L. Birx, Shlomo Maayan, and Guido Ferrari. Immunodominance and Cross-Reactivity of B5703-Restricted CD8 T Lymphocytes from HIV Type 1 Subtype C-Infected Ethiopians. AIDS Res. Hum. Retroviruses, 21(3):239-245, Mar 2005. PubMed ID: 15795531. Show all entries for this paper.


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