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Found 1 matching record:

Displaying record number 53613

HXB2 Location  Gag(141-155)   Gag Epitope Map
View variants at this location
Epitope QMVHQSLSPRTLNAW   Epitope Alignment
Variants
QMtHQnLSPRTLNAW   observed variant
QMVHQaLSPRTLNAW   observed variant
Species (MHC/HLA human

Variant Details

Showing all: 2 variant(s).


Variant ID.  65
Epitope Seq.  QMVHQSLSPRTLNAW
Variant Seq.  QMtHQnLSPRTLNAW
Mutations V/T S/N
Epitope Location V3T S6N
HXB2 Location V143T S146N
Mutation Type OV: observed variant
Method CD8 T-cell Elispot - IFNy
Note The sequence contains a known B7/B8 epitope, but the subjects recognizing it are B7- and B8-negative. The viral sequences isolated from the subjects were qmThqNlsprtlnaw and qmvhqAlsprtlnaw, and the index peptide was recognized.


Variant ID.  66
Epitope Seq.  QMVHQSLSPRTLNAW
Variant Seq.  QMVHQaLSPRTLNAW
Mutations S/A
Epitope Location S6A
HXB2 Location S146A
Mutation Type OV: observed variant
Method CD8 T-cell Elispot - IFNy
Note The sequence contains a known B7/B8 epitope, but the subjects recognizing it are B7- and B8-negative. The viral sequences isolated from the subjects were qmThqNlsprtlnaw and qmvhqAlsprtlnaw, and the index peptide was recognized.

References

Barugahare2005 Banson Barugahare, Chris Baker, Okumu K'Aluoch, Richard Donovan, Mohamed Elrefaei, Mark Eggena, Norman Jones, Steven Mutalya, Cissy Kityo, Peter Mugyenyi, and Huyen Cao. Human Immunodeficiency Virus-Specific Responses in Adult Ugandans: Patterns of Cross-Clade Recognition. J. Virol., 79(7):4132-4139, Apr 2005. PubMed ID: 15767414. Show all entries for this paper.


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