HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 53591

HXB2 Location  Gag(8-18)   Gag Epitope Map
View variants at this location
Epitope LSGGELDRWEK   Epitope Alignment
LSGGkLDaWEK   subtype-specific non-susceptible form
Epitope Name Gag 1.2
Species (MHC/HLA macaque

Variant Details

Showing all: 1 variant(s).

Variant ID.  54
Variant Seq.  LSGGkLDaWEK
Mutations E/K R/A
Epitope Location E5K R8A
HXB2 Location E12K R15A
Mutation Type SNSF: subtype-specific non-susceptible form
Epitope Subtype B
Variant Subtype CRF02_AG
Method Intracellular cytokine staining, T-cell Elispot
Note CRF02 form, LSGGkLDaWEK, does not cross-react with the B clade LSGGELDRWEK elicited response.


Amara2005a Rama Rao Amara, Sunita Sharma, Milloni Patel, James M. Smith, Lakshmi Chennareddi, James G Herndon, and Harriet L. Robinson. Studies on the Cross-Clade and Cross-Species Conservation of HIV-1 Gag-Specific CD8 and CD4 T Cell Responses Elicited by a Clade B DNA/MVA Vaccine in Macaques. Virology, 334(1):124-133, 30 Mar 2005. PubMed ID: 15749128. Show all entries for this paper.

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