HIV molecular immunology database

 

Search the Epitope Variant and Escape Mutation Database

Help


Found 1 matching record:

Displaying record number 52760

HXB2 Location  Gag(162-172)   Gag Epitope Map
View variants at this location
Epitope KAFSPEVIPMF   Epitope Alignment
Variants
KsFSPEVIPMF   observed variant
KgFnPEVIPMF   observed variant
Epitope Name KAF11
Species (MHC/HLA human(B*57:01)

Variant Details

Showing all: 2 variant(s).


Variant ID.  1289
Epitope Seq.  KAFSPEVIPMF
Variant Seq.  KsFSPEVIPMF
Mutations A/S
Epitope Location A2S
HXB2 Location A163S
Mutation Type OV: observed variant
Method Sequence
Note This variant was seen only in one non-progressor and one treated progressor. Index epitope KAF11 is immunodominant in several subjects and highly conserved.


Variant ID.  1290
Epitope Seq.  KAFSPEVIPMF
Variant Seq.  KgFnPEVIPMF
Mutations A/G S/N
Epitope Location A2G S4N
HXB2 Location A163G S165N
Mutation Type OV: observed variant
Method Sequence
Note This variant was seen only in one untreated progressor.

References

Migueles2003 Stephen A. Migueles, Alisha C. Laborico, Hiromi Imamichi, W. Lesley Shupert, Cassandra Royce, Mary McLaughlin, Linda Ehler, Julia Metcalf, Shuying Liu, Claire W. Hallahan, and Mark Connors. The Differential Ability of HLA B*5701+ Long-Term Nonprogressors and Progressors to Restrict Human Immunodeficiency Virus Replication Is Not Caused by Loss of Recognition of Autologous Viral gag Sequences. J. Virol., 77(12):6889-6898, Jun 2003. PubMed ID: 12768008. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health