HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(162-172) | Gag Epitope Map
View variants at this location |
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| Epitope |
KAFSPEVIPMF
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Epitope Alignment | |||||||
| Variants |
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| Epitope Name | KAF11 | ||||||||
| Species (MHC/HLA) | human(B*57:01) | ||||||||
Showing all: 2 variant(s).
| Variant ID. | 1289 |
|---|---|
| Epitope Seq. | KAFSPEVIPMF |
| Variant Seq. | KsFSPEVIPMF |
| Mutations | A/S |
| Epitope Location | A2S |
| HXB2 Location | A163S |
| Mutation Type | OV: observed variant |
| Method | Sequence |
| Note | This variant was seen only in one non-progressor and one treated progressor. Index epitope KAF11 is immunodominant in several subjects and highly conserved. |
| Variant ID. | 1290 |
|---|---|
| Epitope Seq. | KAFSPEVIPMF |
| Variant Seq. | KgFnPEVIPMF |
| Mutations | A/G S/N |
| Epitope Location | A2G S4N |
| HXB2 Location | A163G S165N |
| Mutation Type | OV: observed variant |
| Method | Sequence |
| Note | This variant was seen only in one untreated progressor. |
Migueles2003 Stephen A. Migueles, Alisha C. Laborico, Hiromi Imamichi, W. Lesley Shupert, Cassandra Royce, Mary McLaughlin, Linda Ehler, Julia Metcalf, Shuying Liu, Claire W. Hallahan, and Mark Connors. The Differential Ability of HLA B*5701+ Long-Term Nonprogressors and Progressors to Restrict Human Immunodeficiency Virus Replication Is Not Caused by Loss of Recognition of Autologous Viral gag Sequences. J. Virol., 77(12):6889-6898, Jun 2003. PubMed ID: 12768008. Show all entries for this paper.