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Found 1 matching record:

Displaying record number 52106

HXB2 Location  Gag(84-91)   Gag Epitope Map
View variants at this location
Epitope TLYCVHQR   Epitope Alignment
Variants
TLYCVHQk   susceptible form
TLwCVHQR   observed variant
TLYCVHeR   observed variant
Species (MHC/HLA human(A*11:01)

Variant Details

Showing all: 3 variant(s).


Variant ID.  290
Epitope Seq.  TLYCVHQR
Variant Seq.  TLYCVHQk
Mutations R/K
Epitope Location R8K
HXB2 Location R91K
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Chromium-release assay
Note Variant predominantly found in clade B. There was some CTL activity in PBMC from clade B patients stimulated with this epitope variant.


Variant ID.  291
Epitope Seq.  TLYCVHQR
Variant Seq.  TLwCVHQR
Mutations Y/W
Epitope Location Y3W
HXB2 Location Y86W
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype CRF01_AE
Note Variant predominantly found in clade E.


Variant ID.  292
Epitope Seq.  TLYCVHQR
Variant Seq.  TLYCVHeR
Mutations Q/E
Epitope Location Q7E
HXB2 Location Q90E
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype D
Note Variant predominantly found in clade D.

References

Fukada2002 Katsuhiko Fukada, Hiroko Tomiyama, Chantapong Wasi, Tomoko Matsuda, Shigeru Kusagawa, Hironori Sato, Shinichi Oka, Yutaka Takebe, and Masafumi Takiguchi. Cytotoxic T-cell Recognition of HIV-1 Cross-Clade and Clade-Specific Epitopes in HIV-1-Infected Thai and Japanese Patients. AIDS, 16(5):701-711, 29 Mar 2002. PubMed ID: 11964526. Show all entries for this paper.


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