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Found 1 matching record:

Displaying record number 38

HXB2 Location  Gag(24-31)   Gag Epitope Map
View variants at this location
Epitope GGKKKYKL   Epitope Alignment
Variants
GGKKKYrL   subtype-specific non-susceptible form
GGnKrYrL   subtype-specific non-susceptible form
GGKKKYqL   subtype-specific non-susceptible form
GGKKKYrm   subtype-specific non-susceptible form
GGsKKYKL   subtype-specific non-susceptible form
GGKKtYqL   subtype-specific non-susceptible form
Species (MHC/HLA human(B8)

Variant Details

Showing all: 6 variant(s).


Variant ID.  1104
Epitope Seq.  GGKKKYKL
Variant Seq.  GGKKKYrL
Mutations K/R
Epitope Location K7R
HXB2 Location K30R
Mutation Type SNSF: subtype-specific non-susceptible form
Epitope Subtype B
Method Chromium-release assay
Note This circulating Ugandan variant was not recognized by a CTL clone from a patient infected with Clade B virus.


Variant ID.  1105
Epitope Seq.  GGKKKYKL
Variant Seq.  GGnKrYrL
Mutations K/N K/R K/R
Epitope Location K3N K5R K7R
HXB2 Location K26N K28R K30R
Mutation Type SNSF: subtype-specific non-susceptible form
Epitope Subtype B
Method Chromium-release assay
Note A peptide containing this circulating Ugandan variant was not recognized by a CTL clone from a Clade B-infected patient.


Variant ID.  1106
Epitope Seq.  GGKKKYKL
Variant Seq.  GGKKKYqL
Mutations K/Q
Epitope Location K7Q
HXB2 Location K30Q
Mutation Type SNSF: subtype-specific non-susceptible form
Epitope Subtype B
Method Chromium-release assay
Note A peptide containing this circulating Ugandan variant was not recognized by a CTL clone from a Clade B-infected patient.


Variant ID.  1107
Epitope Seq.  GGKKKYKL
Variant Seq.  GGKKKYrm
Mutations K/R L/M
Epitope Location K7R L8M
HXB2 Location K30R L31M
Mutation Type SNSF: subtype-specific non-susceptible form
Epitope Subtype B
Method Chromium-release assay
Note A peptide containing this circulating Ugandan variant was not recognized by a CTL clone from a Clade B-infected patient.


Variant ID.  1108
Epitope Seq.  GGKKKYKL
Variant Seq.  GGsKKYKL
Mutations K/S
Epitope Location K3S
HXB2 Location K26S
Mutation Type SNSF: subtype-specific non-susceptible form
Epitope Subtype B
Method Chromium-release assay
Note A peptide containing this circulating Ugandan variant was not recognized by a CTL clone from a Clade B-infected patient.


Variant ID.  1109
Epitope Seq.  GGKKKYKL
Variant Seq.  GGKKtYqL
Mutations K/T K/Q
Epitope Location K5T K7Q
HXB2 Location K28T K30Q
Mutation Type SNSF: subtype-specific non-susceptible form
Epitope Subtype B
Method Chromium-release assay
Note A peptide containing this circulating Ugandan variant was not recognized by a CTL clone from a Clade B-infected patient.

References

McAdam1998 S. McAdam, P. Kaleebu, P. Krausa, P. Goulder, N. French, B. Collin, T. Blanchard, J. Whitworth, A. McMichael, and F. Gotch. Cross-Clade Recognition of p55 by Cytotoxic T Lymphocytes in HIV-1 Infection. AIDS, 12:571-579, 1998. PubMed ID: 9583596. Show all entries for this paper.


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