HIV molecular immunology database
Found 1 matching record:
HXB2 Location | Gag(24-31) | Gag Epitope Map
View variants at this location |
|||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epitope |
GGKKKYKL
|
Epitope Alignment | |||||||||||||||||||
Variants |
|
||||||||||||||||||||
Species (MHC/HLA) | human(B8) |
Showing all: 6 variant(s).
Variant ID. | 1104 |
---|---|
Epitope Seq. | GGKKKYKL |
Variant Seq. | GGKKKYrL |
Mutations | K/R |
Epitope Location | K7R |
HXB2 Location | K30R |
Mutation Type | SNSF: subtype-specific non-susceptible form |
Epitope Subtype | B |
Method | Chromium-release assay |
Note | This circulating Ugandan variant was not recognized by a CTL clone from a patient infected with Clade B virus. |
Variant ID. | 1105 |
---|---|
Epitope Seq. | GGKKKYKL |
Variant Seq. | GGnKrYrL |
Mutations | K/N K/R K/R |
Epitope Location | K3N K5R K7R |
HXB2 Location | K26N K28R K30R |
Mutation Type | SNSF: subtype-specific non-susceptible form |
Epitope Subtype | B |
Method | Chromium-release assay |
Note | A peptide containing this circulating Ugandan variant was not recognized by a CTL clone from a Clade B-infected patient. |
Variant ID. | 1106 |
---|---|
Epitope Seq. | GGKKKYKL |
Variant Seq. | GGKKKYqL |
Mutations | K/Q |
Epitope Location | K7Q |
HXB2 Location | K30Q |
Mutation Type | SNSF: subtype-specific non-susceptible form |
Epitope Subtype | B |
Method | Chromium-release assay |
Note | A peptide containing this circulating Ugandan variant was not recognized by a CTL clone from a Clade B-infected patient. |
Variant ID. | 1107 |
---|---|
Epitope Seq. | GGKKKYKL |
Variant Seq. | GGKKKYrm |
Mutations | K/R L/M |
Epitope Location | K7R L8M |
HXB2 Location | K30R L31M |
Mutation Type | SNSF: subtype-specific non-susceptible form |
Epitope Subtype | B |
Method | Chromium-release assay |
Note | A peptide containing this circulating Ugandan variant was not recognized by a CTL clone from a Clade B-infected patient. |
Variant ID. | 1108 |
---|---|
Epitope Seq. | GGKKKYKL |
Variant Seq. | GGsKKYKL |
Mutations | K/S |
Epitope Location | K3S |
HXB2 Location | K26S |
Mutation Type | SNSF: subtype-specific non-susceptible form |
Epitope Subtype | B |
Method | Chromium-release assay |
Note | A peptide containing this circulating Ugandan variant was not recognized by a CTL clone from a Clade B-infected patient. |
Variant ID. | 1109 |
---|---|
Epitope Seq. | GGKKKYKL |
Variant Seq. | GGKKtYqL |
Mutations | K/T K/Q |
Epitope Location | K5T K7Q |
HXB2 Location | K28T K30Q |
Mutation Type | SNSF: subtype-specific non-susceptible form |
Epitope Subtype | B |
Method | Chromium-release assay |
Note | A peptide containing this circulating Ugandan variant was not recognized by a CTL clone from a Clade B-infected patient. |
McAdam1998 S. McAdam, P. Kaleebu, P. Krausa, P. Goulder, N. French, B. Collin, T. Blanchard, J. Whitworth, A. McMichael, and F. Gotch. Cross-Clade Recognition of p55 by Cytotoxic T Lymphocytes in HIV-1 Infection. AIDS, 12:571-579, 1998. PubMed ID: 9583596. Show all entries for this paper.