HIV molecular immunology database
Found 1 matching record:
|HXB2 Location||Gag(183-191)|| Gag Epitope Map
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|Species (MHC/HLA)||human(B14, Cw8)|
Showing all: 1 variant(s).
|Epitope Location||T4M T8I|
|HXB2 Location||T186M T190I|
|Mutation Type||OV: observed variant|
|Note||5/6 Kenyan HEPS subjects recognized this clade B epitope which differed from the clade D variant, DLNmMLNiV.|
RowlandJones1998b S. Rowland-Jones, T. Dong, P. Krausa, J. Sutton, H. Newell, K. Ariyoshi, F. Gotch, S. Sabally, T. Corrah, J. Kimani, K. MacDonald, F. Plummer, J. Ndinya-Achola, H. Whittle, and A. McMichael. The Role of Cytotoxic T Cells in HIV Infection. Dev. Biol. Stand., 92:209-214, 1998. In this paper CTL response to previously defined conserved epitopes was found in exposed but uninfected prostitutes in Nairobi. Subtypes A and D are circulating in this regions, and the reactive epitopes tended to be conserved. Similarly previous studies in the Gambia showed that exposed but uninfected prostitutes tended to have B35 presented CTL epitopes conserved between HIV-1 and HIV-2. It was suggested that what was special about B35 is simply that it presents epitopes found both in HIV-1 and HIV-2. PubMed ID: 9554277. Show all entries for this paper.