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Found 1 matching record:

Displaying record number 1822

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
Variants
SLfNTVATL   escape documented in this paper
SLYNTVAvL   escape documented in this paper
Epitope Name SL9
Species (MHC/HLA human(A2)

Variant Details

Showing all: 2 variant(s).


Variant ID.  383
Epitope Seq.  SLYNTVATL
Variant Seq.  SLfNTVATL
Mutations Y/F
Epitope Location Y3F
HXB2 Location Y79F
Mutation Type E: escape documented in this paper
Note The variant was not recognized by autologous CTL in an infected mother. The variant was transmitted both vertically and horizontally.


Variant ID.  384
Epitope Seq.  SLYNTVATL
Variant Seq.  SLYNTVAvL
Mutations T/V
Epitope Location T8V
HXB2 Location T84V
Mutation Type E: escape documented in this paper
Note A variant found in an infected mother that was vertically transmitted. The wt epitope was not recognized by children's CTLs.

References

Goulder2001b P. J. Goulder, C. Pasquier, E. C. Holmes, B. Liang, Y. Tang, J. Izopet, K. Saune, E. S. Rosenberg, S. K. Burchett, K. McIntosh, M. Barnardo, M. Bunce, B. D. Walker, C. Brander, and R. E. Phillips. Mother-to-child transmission of HIV infection and CTL escape through HLA-A2-SLYNTVATL epitope sequence variation. Immunol. Lett., 79(1-2):109-16, 1 Nov 2001. PubMed ID: 11595297. Show all entries for this paper.


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