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Displaying record number 1822

HXB2 Location Gag(77-85) Gag Epitope Map
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SLYNTVATL

`SLfNTVATL`		escape documented in this paper
`SLYNTVAvL`		escape documented in this paper

Epitope Name SL9

Species (MHC/HLA) human(A2)

Variant Details

Showing all: 2 variant(s).

Variant ID.	`383`
Epitope Seq.	`SLYNTVATL`
Variant Seq.	`SLfNTVATL`
Mutations	Y/F
Epitope Location	Y3F
HXB2 Location	Y79F
Mutation Type	E: escape documented in this paper
Note	The variant was not recognized by autologous CTL in an infected mother. The variant was transmitted both vertically and horizontally.

Variant ID.	`384`
Epitope Seq.	`SLYNTVATL`
Variant Seq.	`SLYNTVAvL`
Mutations	T/V
Epitope Location	T8V
HXB2 Location	T84V
Mutation Type	E: escape documented in this paper
Note	A variant found in an infected mother that was vertically transmitted. The wt epitope was not recognized by children's CTLs.

References

Goulder2001b P. J. Goulder, C. Pasquier, E. C. Holmes, B. Liang, Y. Tang, J. Izopet, K. Saune, E. S. Rosenberg, S. K. Burchett, K. McIntosh, M. Barnardo, M. Bunce, B. D. Walker, C. Brander, and R. E. Phillips. Mother-to-child transmission of HIV infection and CTL escape through HLA-A2-SLYNTVATL epitope sequence variation. Immunol. Lett., 79(1-2):109-16, 1 Nov 2001. PubMed ID: 11595297. Show all entries for this paper.