HIV molecular immunology database

 

Search the Epitope Variant and Escape Mutation Database

Help


Found 1 matching record:

Displaying record number 1819

HXB2 Location  Gag(19-27)   Gag Epitope Map
View variants at this location
Epitope IRLRPGGKK   Epitope Alignment
Variants
IRLRPGrKK   observed variant
IRLRPrrKK   observed variant
IRkRPGGKK   observed variant
IRLgPGGsK   inferred escape
IRLRPGGsK   inferred escape
Epitope Name IK9
Species (MHC/HLA human(B27)

Variant Details

Showing all: 5 variant(s).


Variant ID.  385
Epitope Seq.  IRLRPGGKK
Variant Seq.  IRLRPGrKK
Mutations G/R
Epitope Location G7R
HXB2 Location G25R
Mutation Type OV: observed variant
Note Variant found in one B27 positive child in 4/11 clones, but not in its B27 positive mother


Variant ID.  386
Epitope Seq.  IRLRPGGKK
Variant Seq.  IRLRPrrKK
Mutations G/R G/R
Epitope Location G6R G7R
HXB2 Location G24R G25R
Mutation Type OV: observed variant
Note Variant found in one B27 positive child in 1/11 clones, but not in its B27 positive mother


Variant ID.  387
Epitope Seq.  IRLRPGGKK
Variant Seq.  IRkRPGGKK
Mutations L/K
Epitope Location L3K
HXB2 Location L21K
Mutation Type OV: observed variant
Note Variant found in one B27 positive child in 1/19 clones, but not in its B27 positive mother


Variant ID.  388
Epitope Seq.  IRLRPGGKK
Variant Seq.  IRLgPGGsK
Mutations R/G K/S
Epitope Location R4G K8S
HXB2 Location R22G K26S
Mutation Type IE: inferred escape
Note Author tabulates this variant found in one B27 positive child in 1/8 clones, and in its B27 positive mother in 1/10 clones as an escape variant.


Variant ID.  389
Epitope Seq.  IRLRPGGKK
Variant Seq.  IRLRPGGsK
Mutations K/S
Epitope Location K8S
HXB2 Location K26S
Mutation Type IE: inferred escape
Note Variant found in one B27 positive child in 7/8 clones, and in its B27 positive mother in 9/10 clones.

References

Goulder2001c P. J. Goulder, C. Brander, Y. Tang, C. Tremblay, R. A. Colbert, M. M. Addo, E. S. Rosenberg, T. Nguyen, R. Allen, A. Trocha, M. Altfeld, S. He, M. Bunce, R. Funkhouser, S. I. Pelton, S. K. Burchett, K. McIntosh, B. T. Korber, and B. D. Walker. Evolution and transmission of stable CTL escape mutations in HIV infection. Nature, 412(6844):334-8, 19 Jul 2001. PubMed ID: 11460164. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health