HIV molecular immunology database

 

Search the Epitope Variant and Escape Mutation Database

Help


Found 1 matching record:

Displaying record number 1756

HXB2 Location  Gag(28-36)   Gag Epitope Map
View variants at this location
Epitope KYKLKHIVW   Epitope Alignment
Variants
KYKmKHlVW   subtype-specific non-susceptible form
Species (MHC/HLA human(A*24)

Variant Details

Showing all: 1 variant(s).


Variant ID.  87
Epitope Seq.  KYKLKHIVW
Variant Seq.  KYKmKHlVW
Mutations L/M I/L
Epitope Location L4M I7L
HXB2 Location L31M I34L
Mutation Type SNSF: subtype-specific non-susceptible form
Epitope Subtype B
Variant Subtype CRF01_AE
Method Chromium-release assay, HLA binding
Note The HLA-A24 subjects tested did not recognize the E clade version KYKmKHlVW, which differs from the previously defined B clade version KYKLKHIVW by two amino acids.

References

Bond2001 K. B. Bond, B. Sriwanthana, T. W. Hodge, A. S. De Groot, T. D. Mastro, N. L. Young, N. Promadej, J. D. Altman, K. Limpakarnjanarat, and J. M. McNicholl. An HLA-directed molecular and bioinformatics approach identifies new HLA-A11 HIV-1 subtype E cytotoxic T lymphocyte epitopes in HIV-1-infected Thais. AIDS Res. Hum. Retroviruses, 17(8):703-17, 20 May 2001. PubMed ID: 11429111. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health