HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(77-85) | Gag Epitope Map
View variants at this location |
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Epitope |
SLYNTVATL
|
Epitope Alignment | |||||||||||||
| Variants |
|
||||||||||||||
| Epitope Name | SL9 | ||||||||||||||
| Species (MHC/HLA) | human(A2) | ||||||||||||||
Showing all: 4 variant(s).
| Variant ID. | 408 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLfNTVATL |
| Mutations | Y/F |
| Epitope Location | Y3F |
| HXB2 Location | Y79F |
| Mutation Type | SF: susceptible form |
| Method | Chromium-release assay |
| Note | No variants were found in the patient, but this synthetic variant was tested against patient CTLs. The variant was recognized by CTLs and induced target specific lysis. |
| Variant ID. | 409 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLYNTiATL |
| Mutations | V/I |
| Epitope Location | V6I |
| HXB2 Location | V82I |
| Mutation Type | SF: susceptible form |
| Method | Chromium-release assay |
| Note | No variants were found in the patient, but this synthetic variant was tested against patient CTLs. The variant was recognized by CTLs and induced target specific lysis. |
| Variant ID. | 410 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLYNTVAvL |
| Mutations | T/V |
| Epitope Location | T8V |
| HXB2 Location | T84V |
| Mutation Type | SF: susceptible form |
| Method | Chromium-release assay |
| Note | No variants were found in the patient, but this synthetic variant was tested against patient CTLs. The variant was recognized by CTLs and induced target specific lysis. |
| Variant ID. | 411 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLYNaVATL |
| Mutations | T/A |
| Epitope Location | T5A |
| HXB2 Location | T81A |
| Mutation Type | SF: susceptible form |
| Method | Chromium-release assay |
| Note | No variants were found in the patient, but this synthetic variant was tested against patient CTLs. The variant was recognized by CTLs and induced target specific lysis. |
Harrer1998 T. Harrer, E. Harrer, P. Barbosa, F. Kaufmann, R. Wagner, S. Bruggemann, J. R. Kalden, M. Feinberg, R. P. Johnson, S. Buchbinder, and B. D. Walker. Recognition of Two Overlapping CTL Epitopes in HIV-1 p17 by CTL from a Long-Term Nonprogressing HIV-1-Infected Individual. J. Immunol., 161:4875-4881, 1998. PubMed ID: 9794421. Show all entries for this paper.