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Displaying record number 864

HXB2 Location gp160(770-780) gp160 Epitope Map
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RLRDLLLIVTR

`RLRDfiLIVTR`		diminished response; subtype-specific susceptible form
`SLRDLLLIVTR`		diminished response; subtype-specific susceptible form

Species (MHC/HLA) human(A3)

Variant Details

Showing all: 2 variant(s).

Variant ID.	`106`
Epitope Seq.	`RLRDLLLIVTR`
Variant Seq.	`RLRDfiLIVTR`
Mutations	L/F L/I
Epitope Location	L5F L6I
HXB2 Location	L774F L775I
Mutation Type	DR: diminished response SSF: subtype-specific susceptible form
Epitope Subtype	B
Variant Subtype	A, C, CRF01_AE
Method	Chromium-release assay
Note	The consensus peptide of clade B is RLRDLLLIVTR. The consensus peptide of clades A, C and E is RLRDFILIVTR and it is less reactive.

Variant ID.	`107`
Epitope Seq.	`RLRDLLLIVTR`
Variant Seq.	`SLRDLLLIVTR`
Mutations	R/S
Epitope Location	R1S
HXB2 Location	R770S
Mutation Type	DR: diminished response SSF: subtype-specific susceptible form
Epitope Subtype	B
Variant Subtype	D
Method	Chromium-release assay
Note	The consensus peptide of clade B is RLRDLLLIVTR. The consensus peptide of clade D is SLRDLLLIVTR and it is less reactive.

References

Cao1997a H. Cao, P. Kanki, J. L. Sankale, A. Dieng-Sarr, Gail P. Mazzara, S. Kalams, B. Korber, S. M'Boup, and B. D. Walker. CTL Cross-Reactivity among Different HIV-1 Clades: Implications for Vaccine Development. J. Virol., 71:8615-8623, 1997. PubMed ID: 9343219. Show all entries for this paper.