HIV molecular immunology database
Found 1 matching record:
HXB2 Location | gp160(770-780) | gp160 Epitope Map
View variants at this location |
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Epitope |
RLRDLLLIVTR
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Epitope Alignment | |||||||
Variants |
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Species (MHC/HLA) | human(A3) |
Showing all: 2 variant(s).
Variant ID. | 106 |
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Epitope Seq. | RLRDLLLIVTR |
Variant Seq. | RLRDfiLIVTR |
Mutations | L/F L/I |
Epitope Location | L5F L6I |
HXB2 Location | L774F L775I |
Mutation Type | DR: diminished response SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | A, C, CRF01_AE |
Method | Chromium-release assay |
Note | The consensus peptide of clade B is RLRDLLLIVTR. The consensus peptide of clades A, C and E is RLRDFILIVTR and it is less reactive. |
Variant ID. | 107 |
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Epitope Seq. | RLRDLLLIVTR |
Variant Seq. | SLRDLLLIVTR |
Mutations | R/S |
Epitope Location | R1S |
HXB2 Location | R770S |
Mutation Type | DR: diminished response SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | D |
Method | Chromium-release assay |
Note | The consensus peptide of clade B is RLRDLLLIVTR. The consensus peptide of clade D is SLRDLLLIVTR and it is less reactive. |
Cao1997a H. Cao, P. Kanki, J. L. Sankale, A. Dieng-Sarr, Gail P. Mazzara, S. Kalams, B. Korber, S. M'Boup, and B. D. Walker. CTL Cross-Reactivity among Different HIV-1 Clades: Implications for Vaccine Development. J. Virol., 71:8615-8623, 1997. PubMed ID: 9343219. Show all entries for this paper.