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Found 1 matching record:

Displaying record number 788

HXB2 Location  gp160(416-424)   gp160 Epitope Map
View variants at this location
Epitope LPCRIKQII   Epitope Alignment
Variants
LlCRIKQII   observed variant
LqCRIKQII   observed variant
LgCRIKQII   observed variant
LsCRIKQII   observed variant
LqCkIKQII   observed variant
LqCkIrQIv   observed variant
LqCRIKQIv   observed variant
LPCkIKQII   observed variant
LPCRtKQII   observed variant
LPCRIrQII   observed variant
LPCRIsQII   observed variant
LPCRIrQfv   observed variant
LPCRIKeII   observed variant
LPCRIKQfI   observed variant
LPCRIKQvI   observed variant
LPCRIKQfv   observed variant
LPCRIKQIv   observed variant
LPCRIKQIl   observed variant
LqCRIKQfI   observed variant
Species (MHC/HLA human(B*5101)

Variant Details

Showing all: 19 variant(s).


Variant ID.  1770
Epitope Seq.  LPCRIKQII
Variant Seq.  LlCRIKQII
Mutations P/L
Epitope Location P2L
HXB2 Location P417L
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 1/104 Clade B strain sequences carried this 2L variant. Challenge epitope elicited CTL response in 1 of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength. Variant not tested.


Variant ID.  1771
Epitope Seq.  LPCRIKQII
Variant Seq.  LqCRIKQII
Mutations P/Q
Epitope Location P2Q
HXB2 Location P417Q
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 8/104 Clade B strain sequences carried this 2Q variant. Challenge epitope elicited CTL response in 1 of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength. Variant not tested.


Variant ID.  1772
Epitope Seq.  LPCRIKQII
Variant Seq.  LgCRIKQII
Mutations P/G
Epitope Location P2G
HXB2 Location P417G
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 1/104 Clade B strain sequences carried this 2G variant. Challenge epitope elicited CTL response in 1 of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength. Variant not tested.


Variant ID.  1773
Epitope Seq.  LPCRIKQII
Variant Seq.  LsCRIKQII
Mutations P/S
Epitope Location P2S
HXB2 Location P417S
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 1/104 Clade B strain sequences carried this 2S variant. Challenge epitope elicited CTL response in 1 of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength. Variant not tested.


Variant ID.  1774
Epitope Seq.  LPCRIKQII
Variant Seq.  LqCkIKQII
Mutations P/Q R/K
Epitope Location P2Q R4K
HXB2 Location P417Q R419K
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 1/104 Clade B strain sequences carried this 2Q4K variant. Index epitope elicited CTL response in 1 of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength. Variant not tested.


Variant ID.  1775
Epitope Seq.  LPCRIKQII
Variant Seq.  LqCkIrQIv
Mutations P/Q R/K K/R I/V
Epitope Location P2Q R4K K6R I9V
HXB2 Location P417Q R419K K421R I424V
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 1/104 Clade B strain sequences carried this 2Q4K6R9V variant. Challenge epitope elicited CTL response in 1 of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength. Variant not tested.


Variant ID.  1777
Epitope Seq.  LPCRIKQII
Variant Seq.  LqCRIKQIv
Mutations P/Q I/V
Epitope Location P2Q I9V
HXB2 Location P417Q I424V
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 3/104 Clade B strain sequences carried this 2Q9V variant. Challenge epitope elicited CTL response in 1 of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength. Variant not tested.


Variant ID.  1778
Epitope Seq.  LPCRIKQII
Variant Seq.  LPCkIKQII
Mutations R/K
Epitope Location R4K
HXB2 Location R419K
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 2/104 Clade B strain sequences carried this 4K variant. Challenge epitope elicited CTL response in 1 of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength. Variant not tested.


Variant ID.  1779
Epitope Seq.  LPCRIKQII
Variant Seq.  LPCRtKQII
Mutations I/T
Epitope Location I5T
HXB2 Location I420T
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 1/104 Clade B strain sequences carried this 5T variant. Index epitope elicited CTL response in 1 of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength.


Variant ID.  1780
Epitope Seq.  LPCRIKQII
Variant Seq.  LPCRIrQII
Mutations K/R
Epitope Location K6R
HXB2 Location K421R
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 2/104 Clade B strain sequences carried this 6R variant. Challenge epitope elicited CTL response in 1of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength. Variant not tested.


Variant ID.  1781
Epitope Seq.  LPCRIKQII
Variant Seq.  LPCRIsQII
Mutations K/S
Epitope Location K6S
HXB2 Location K421S
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 1/104 Clade B strain sequences carried this 6S variant. Challenge epitope elicited CTL response in 1 of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength. Variant not tested.


Variant ID.  1782
Epitope Seq.  LPCRIKQII
Variant Seq.  LPCRIrQfv
Mutations K/R I/F I/V
Epitope Location K6R I8F I9V
HXB2 Location K421R I423F I424V
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 1/104 Clade B strain sequences carried this 6R8F9V variant. Challenge epitope elicited CTL response in 1 of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength. Variant not tested.


Variant ID.  1783
Epitope Seq.  LPCRIKQII
Variant Seq.  LPCRIKeII
Mutations Q/E
Epitope Location Q7E
HXB2 Location Q422E
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 1/104 Clade B strain sequences carried this 7E variant. Challenge epitope elicited CTL response in 1 of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength.


Variant ID.  1784
Epitope Seq.  LPCRIKQII
Variant Seq.  LPCRIKQfI
Mutations I/F
Epitope Location I8F
HXB2 Location I423F
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 4/104 Clade B strain sequences carried this 8F variant. Challenge epitope elicited CTL response in 1 of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength. Variant not tested.


Variant ID.  1785
Epitope Seq.  LPCRIKQII
Variant Seq.  LPCRIKQvI
Mutations I/V
Epitope Location I8V
HXB2 Location I423V
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 3/104 Clade B strain sequences carried this 8V variant. Challenge epitope elicited CTL response in 1 of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength. Variant not tested.


Variant ID.  1786
Epitope Seq.  LPCRIKQII
Variant Seq.  LPCRIKQfv
Mutations I/F I/V
Epitope Location I8F I9V
HXB2 Location I423F I424V
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 1/104 Clade B strain sequences carried this 8F9V variant. Challenge epitope elicited CTL response in 1 of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength. Variant not tested.


Variant ID.  1787
Epitope Seq.  LPCRIKQII
Variant Seq.  LPCRIKQIv
Mutations I/V
Epitope Location I9V
HXB2 Location I424V
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 19/104 Clade B strain sequences carried this 9V variant. Challenge epitope elicited CTL response in 1 of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength. Variant not tested.


Variant ID.  1788
Epitope Seq.  LPCRIKQII
Variant Seq.  LPCRIKQIl
Mutations I/L
Epitope Location I9L
HXB2 Location I424L
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 1/104 Clade B strain sequences carried this 9L variant. Challenge epitope elicited CTL response in 1 of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength. Variant not tested.


Variant ID.  2265
Epitope Seq.  LPCRIKQII
Variant Seq.  LqCRIKQfI
Mutations P/Q I/F
Epitope Location P2Q I8F
HXB2 Location P417Q I423F
Mutation Type OV: observed variant
Method Chromium-release assay, HLA binding
Note 1/104 Clade B strain sequences carried this 2Q8F variant. Challenge epitope elicited CTL response in 1 of 3 HLA-B51 seropositive individuals, and bound HLA-B*5101 with high strength. Variant not tested.

References

Tomiyama1999 H. Tomiyama, T. Sakaguchi, K. Miwa, S. Oka, A. Iwamoto, Y. Kaneko, and M. Takiguchi. Identification of multiple HIV-1 CTL epitopes presented by HLA-B*5101. Hum. Immunol., 60:177-86, 1999. PubMed ID: 10321954. Show all entries for this paper.


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