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Displaying record number 62676

HXB2 Location  Gag(263-272)   Gag Epitope Map
View variants at this location
Epitope KRWIILGLNK   Epitope Alignment
Variants
{n}KRWIILGLNK  
{d}KRWIILGLNK  
{s}KRWIILGLNK  
{p}KRWIILGLNK  
{i}KRWIILGLNK  
{w}KRWIILGLNK  
{k}KRWIILGLNK  
{a}KRWIILGLNK  
{m}KRWIILGLNK  
{l}KRWIILGLNK  
{r}KRWIILGLNK  
{q}KRWIILGLNK  
{e}KRWIILGLNK  
{v}KRWIILGLNK  
{t}KRWIILGLNK  
{g}KRWIILGLNK  
KRWIILGLNK{l}  
KRWIILGLNK{r}  
KRWIILGLNK{k}  
KRWIILGLNK{v}  
KRWIILGLNK{t}  
KRWIILGLNK{m}  
KRWIILGLNK{c}  
KRWIILGLNK{w}  
KRWIILGLNK{p}  
KRWIILGLNK{s}  
KRWIILGLNK{q}  
KRWIILGLNK{g}  
KRWIILGLNa  
KRWIILGLNK{a}  
KRlIILGLNK  
KRcIILGLNK  
KRWIIiGLNK  
KRWIImGLNK  
KRWvILGLNK  
KRWIIvGLNK  
KnWIILGLNK  
KRWIIpGLNK  
KRWIILwLNK  
KRWIILvLNK  
KRWIILeLNK  
KRWIILrLNK  
KRrIILGLNK  
KRsIILGLNK  
KRWtILGLNK  
nRWIILGLNK  
eRWIILGLNK  
KRWIILGsNK  
KRWIILGpNK  
KmWIILGLNK  
KRWIILGLNe  
KRWIILGLNr  
rRWIILGLNK  
KRgIILGLNK  
KRWIIrGLNK  
KRWIItGLNK  
KRWIILGLkK  
KRWIvLGLNK  
KRWIILaLNK  
KRWIILGvNK  
KRWIILGmNK  
KRWIILGwNK  
KkWIILGLNK  
KcWIILGLNK  
KRWaILGLNK  
KRWIlLGLNK  
KRWIIfGLNK  
KRWIIqGLNK  
KRWIIwGLNK  
KRWIILGLsK  
KRWItLGLNK  
KwWIILGLNK  
KgWIILGLNK  
KtWIILGLNK  
KsWIILGLNK  
KaWIILGLNK  
KqWIILGLNK  
KlWIILGLNK  
KRWImLGLNK  
KRWIcLGLNK  
KRWIIcGLNK  
KRWIIsGLNK  
KRWIIaGLNK  
KRWIIsGLlK  
KRWIIqGLaK  
KRWIInGLiK  
KRWIILGLgK  
KRWIILGLqK  
KRWIILGLhK  
KRWIILGLtK  
KRWlILGLNK  
KRWcILGLNK  
KRWIsLGLNK  
KRWsILGLNK  
KRWrILGLNK  
KRaIILGLNK  
KRWIgLGLNK  
KRWIaLGLNK  
KeWIILGLNK  
KRWIILGLNt  
hRWIILGLNK  
vRWIILGLNK  
KRWIILtLNK  
eRWIILGLNK  
fRWIILGLNK  
dRWIILGLNK  
sRWIILGLNK  
pRWIILGLNK  
wRWIILGLNK  
cRWIILGLNK  
lRWIILGLNK  
aRWIILGLNK  
sRWIILGLNK  
qRWIILGLNK  
gRWIILGLNK  
mRWIILGLNK  
KpWIILGLNK  
KvWIILGLNK  
KRvIILGLNK  
KRWpILGLNK  
KRWwILGLNK  
KRWgILGLNK  
KRWIrLGLNK  
KRWIIkGLNK  
KRWIILGLNe  
KRWIIeGLNK  
KRWIIgGLNK  
KRWIILlLNK  
KRWIILsLNK  
KRWIILGtNK  
KRWIILGeNK  
KRWIILGgNK  
KRWIILGaNK  
KRWIILGrNK  
KRWIILGLpK  
KRWIILGLwK  
KRWIILGLvK  
KRWIILGLaK  
KRWIILGLlK  
KRWIILGLrK  
KRWIILGLNm  
KRWIILGLNv  
KRWIILGLNp  
KRWIILGLNl  
KRWIILGLNq  
KRWIILGLNw  
KRWIILGLNg  
KRWIILGLmK  
Epitope Name KK10
Species (MHC/HLA human(B*27:05)

Variant Details

Showing all: 148 variant(s).


Variant ID.  4707
Epitope Seq.  {Y}KRWIILGLNK
Variant Seq.  {n}KRWIILGLNK
Mutations Y/N
Epitope Location Y-1N
HXB2 Location Y262N
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, nKRWIILGLNK (-1 to the start of epitope KK10) had a decreased replicative capacity.


Variant ID.  4708
Epitope Seq.  {Y}KRWIILGLNK
Variant Seq.  {d}KRWIILGLNK
Mutations Y/D
Epitope Location Y-1D
HXB2 Location Y262D
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, dKRWIILGLNK (-1 to the start of epitope KK10) had a substantially decreased replicative capacity.


Variant ID.  4709
Epitope Seq.  {Y}KRWIILGLNK
Variant Seq.  {s}KRWIILGLNK
Mutations Y/S
Epitope Location Y-1S
HXB2 Location Y262S
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, sKRWIILGLNK (-1 to the start of epitope KK10) had a substantially decreased replicative capacity.


Variant ID.  4710
Epitope Seq.  {Y}KRWIILGLNK
Variant Seq.  {p}KRWIILGLNK
Mutations Y/P
Epitope Location Y-1P
HXB2 Location Y262P
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, pKRWIILGLNK (-1 to the start of epitope KK10) had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4711
Epitope Seq.  {Y}KRWIILGLNK
Variant Seq.  {i}KRWIILGLNK
Mutations Y/I
Epitope Location Y-1I
HXB2 Location Y262I
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, iKRWIILGLNK (-1 to the start of epitope KK10) had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4712
Epitope Seq.  {Y}KRWIILGLNK
Variant Seq.  {w}KRWIILGLNK
Mutations Y/W
Epitope Location Y-1W
HXB2 Location Y262W
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, wKRWIILGLNK (-1 to the start of epitope KK10) had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4713
Epitope Seq.  {Y}KRWIILGLNK
Variant Seq.  {k}KRWIILGLNK
Mutations Y/K
Epitope Location Y-1K
HXB2 Location Y262K
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, kKRWIILGLNK (-1 to the start of epitope KK10) had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4714
Epitope Seq.  {Y}KRWIILGLNK
Variant Seq.  {a}KRWIILGLNK
Mutations Y/A
Epitope Location Y-1A
HXB2 Location Y262A
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, aKRWIILGLNK (-1 to the start of epitope KK10) had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4715
Epitope Seq.  {Y}KRWIILGLNK
Variant Seq.  {m}KRWIILGLNK
Mutations Y/M
Epitope Location Y-1M
HXB2 Location Y262M
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, mKRWIILGLNK (-1 to the start of epitope KK10) had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4716
Epitope Seq.  {Y}KRWIILGLNK
Variant Seq.  {l}KRWIILGLNK
Mutations Y/L
Epitope Location Y-1L
HXB2 Location Y262L
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, lKRWIILGLNK (-1 to the start of epitope KK10) had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4717
Epitope Seq.  {Y}KRWIILGLNK
Variant Seq.  {r}KRWIILGLNK
Mutations Y/R
Epitope Location Y-1R
HXB2 Location Y262R
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, rKRWIILGLNK (-1 to the start of epitope KK10) had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4718
Epitope Seq.  {Y}KRWIILGLNK
Variant Seq.  {q}KRWIILGLNK
Mutations Y/Q
Epitope Location Y-1Q
HXB2 Location Y262Q
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, qKRWIILGLNK (-1 to the start of epitope KK10) had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4719
Epitope Seq.  {Y}KRWIILGLNK
Variant Seq.  {e}KRWIILGLNK
Mutations Y/E
Epitope Location Y-1E
HXB2 Location Y262E
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, eKRWIILGLNK (-1 to the start of epitope KK10) had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4720
Epitope Seq.  {Y}KRWIILGLNK
Variant Seq.  {v}KRWIILGLNK
Mutations Y/V
Epitope Location Y-1V
HXB2 Location Y262V
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, vKRWIILGLNK (-1 to the start of epitope KK10) had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4721
Epitope Seq.  {Y}KRWIILGLNK
Variant Seq.  {t}KRWIILGLNK
Mutations Y/T
Epitope Location Y-1T
HXB2 Location Y262T
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, tKRWIILGLNK (-1 to the start of epitope KK10) had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4722
Epitope Seq.  {Y}KRWIILGLNK
Variant Seq.  {g}KRWIILGLNK
Mutations Y/G
Epitope Location Y-1G
HXB2 Location Y262G
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, gKRWIILGLNK (-1 to the start of epitope KK10) had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4723
Epitope Seq.  KRWIILGLNK{I}
Variant Seq.  KRWIILGLNK{l}
Mutations I/L
Epitope Location I+1L
HXB2 Location I273L
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNKl (+1 to the end of epitope KK10) had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4724
Epitope Seq.  KRWIILGLNK{I}
Variant Seq.  KRWIILGLNK{r}
Mutations I/R
Epitope Location I+1R
HXB2 Location I273R
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNKr (+1 to the end of epitope KK10) had at least a 2-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4725
Epitope Seq.  KRWIILGLNK{I}
Variant Seq.  KRWIILGLNK{k}
Mutations I/K
Epitope Location I+1K
HXB2 Location I273K
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNKk (+1 to the end of epitope KK10) had at least a 5-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4726
Epitope Seq.  KRWIILGLNK{I}
Variant Seq.  KRWIILGLNK{v}
Mutations I/V
Epitope Location I+1V
HXB2 Location I273V
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNKv (+1 to the end of epitope KK10) had at least a 2-fold increase in relative enrichment, when cultured with 1 of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4727
Epitope Seq.  KRWIILGLNK{I}
Variant Seq.  KRWIILGLNK{t}
Mutations I/T
Epitope Location I+1T
HXB2 Location I273T
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNKt (+1 to the end of epitope KK10) had a decreased replicative capacity.


Variant ID.  4728
Epitope Seq.  KRWIILGLNK{I}
Variant Seq.  KRWIILGLNK{m}
Mutations I/M
Epitope Location I+1M
HXB2 Location I273M
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNKm (+1 to the end of epitope KK10) had a decreased replicative capacity.


Variant ID.  4729
Epitope Seq.  KRWIILGLNK{I}
Variant Seq.  KRWIILGLNK{c}
Mutations I/C
Epitope Location I+1C
HXB2 Location I273C
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNKc (+1 to the end of epitope KK10) had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4730
Epitope Seq.  KRWIILGLNK{I}
Variant Seq.  KRWIILGLNK{w}
Mutations I/W
Epitope Location I+1W
HXB2 Location I273W
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNKw (+1 to the end of epitope KK10) had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4731
Epitope Seq.  KRWIILGLNK{I}
Variant Seq.  KRWIILGLNK{p}
Mutations I/P
Epitope Location I+1P
HXB2 Location I273P
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNKp (+1 to the end of epitope KK10) had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4732
Epitope Seq.  KRWIILGLNK{I}
Variant Seq.  KRWIILGLNK{s}
Mutations I/S
Epitope Location I+1S
HXB2 Location I273S
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNKs (+1 to the end of epitope KK10) had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4733
Epitope Seq.  KRWIILGLNK{I}
Variant Seq.  KRWIILGLNK{q}
Mutations I/Q
Epitope Location I+1Q
HXB2 Location I273Q
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNKq (+1 to the end of epitope KK10) had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4734
Epitope Seq.  KRWIILGLNK{I}
Variant Seq.  KRWIILGLNK{g}
Mutations I/G
Epitope Location I+1G
HXB2 Location I273G
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNKg (+1 to the end of epitope KK10) had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4735
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLNa
Mutations K/A
Epitope Location K10A
HXB2 Location K272A
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNa had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4736
Epitope Seq.  KRWIILGLNK{I}
Variant Seq.  KRWIILGLNK{a}
Mutations I/A
Epitope Location I+1A
HXB2 Location I273A
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNKa (+1 to the end of epitope KK10) had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4737
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRlIILGLNK
Mutations W/L
Epitope Location W3L
HXB2 Location W265L
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRlIILGLNK had a slightly increased replicative capacity but did not have an increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs.


Variant ID.  4738
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRcIILGLNK
Mutations W/C
Epitope Location W3C
HXB2 Location W265C
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRcIILGLNK had a slightly increased replicative capacity but did not have an increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs.


Variant ID.  4739
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIIiGLNK
Mutations L/I
Epitope Location L6I
HXB2 Location L268I
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIIiGLNK had at least a 2-fold increase in relative enrichment, when cultured with 1 of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs.


Variant ID.  4740
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIImGLNK
Mutations L/M
Epitope Location L6M
HXB2 Location L268M
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIImGLNK had at least a 2-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs.


Variant ID.  4741
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWvILGLNK
Mutations I/V
Epitope Location I4V
HXB2 Location I266V
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWvILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, and only a moderate reduction in replicative capacity. This suggests escape mutant potential as defined by the authors.


Variant ID.  4742
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIIvGLNK
Mutations L/V
Epitope Location L6V
HXB2 Location L268V
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIIvGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs and only a moderate reduction in replicative capacity. This suggests escape mutant potential as defined by the authors.


Variant ID.  4743
Epitope Seq.  KRWIILGLNK
Variant Seq.  KnWIILGLNK
Mutations R/N
Epitope Location R2N
HXB2 Location R264N
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KnWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs and only a moderate reduction in replicative capacity. This suggests escape mutant potential as defined by the authors.


Variant ID.  4744
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIIpGLNK
Mutations L/P
Epitope Location L6P
HXB2 Location L268P
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIIpGLNK had a decreased replicative capacity.


Variant ID.  4745
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILwLNK
Mutations G/W
Epitope Location G7W
HXB2 Location G269W
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILwLNK had a decreased replicative capacity.


Variant ID.  4746
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILvLNK
Mutations G/V
Epitope Location G7V
HXB2 Location G269V
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILvLNK had a decreased replicative capacity.


Variant ID.  4747
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILeLNK
Mutations G/E
Epitope Location G7E
HXB2 Location G269E
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILeLNK had a decreased replicative capacity.


Variant ID.  4748
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILrLNK
Mutations G/R
Epitope Location G7R
HXB2 Location G269R
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILrLNK had a decreased replicative capacity.


Variant ID.  4749
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRrIILGLNK
Mutations W/R
Epitope Location W3R
HXB2 Location W265R
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRrIILGLNK had a decreased replicative capacity.


Variant ID.  4750
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRsIILGLNK
Mutations W/S
Epitope Location W3S
HXB2 Location W265S
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRsIILGLNK had a decreased replicative capacity.


Variant ID.  4751
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWtILGLNK
Mutations I/T
Epitope Location I4T
HXB2 Location I266T
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWtILGLNK had a decreased replicative capacity.


Variant ID.  4752
Epitope Seq.  KRWIILGLNK
Variant Seq.  nRWIILGLNK
Mutations K/N
Epitope Location K1N
HXB2 Location K263N
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, nRWIILGLNK had a decreased replicative capacity.


Variant ID.  4753
Epitope Seq.  KRWIILGLNK
Variant Seq.  eRWIILGLNK
Mutations K/E
Epitope Location K1E
HXB2 Location K263E
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, eRWIILGLNK had a decreased replicative capacity.


Variant ID.  4754
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGsNK
Mutations L/S
Epitope Location L8S
HXB2 Location L270S
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGsNK had a decreased replicative capacity.


Variant ID.  4755
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGpNK
Mutations L/P
Epitope Location L8P
HXB2 Location L270P
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGpNK had a decreased replicative capacity.


Variant ID.  4756
Epitope Seq.  KRWIILGLNK
Variant Seq.  KmWIILGLNK
Mutations R/M
Epitope Location R2M
HXB2 Location R264M
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KmWIILGLNK had at least a 2-fold increase in relative enrichment, when cultured with 1 of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4757
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLNe
Mutations K/E
Epitope Location K10E
HXB2 Location K272E
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNe had at least a 2-fold increase in relative enrichment, when cultured with 1 of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4758
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLNr
Mutations K/R
Epitope Location K10R
HXB2 Location K272R
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNr had at least a 2-fold increase in relative enrichment, when cultured with 1 of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4759
Epitope Seq.  KRWIILGLNK
Variant Seq.  rRWIILGLNK
Mutations K/R
Epitope Location K1R
HXB2 Location K263R
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, rRWIILGLNK had at least a 2-fold increase in relative enrichment, when cultured with 1 of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4760
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRgIILGLNK
Mutations W/G
Epitope Location W3G
HXB2 Location W265G
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRgIILGLNK had at least a 2-fold increase in relative enrichment, when cultured with 1 of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4761
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIIrGLNK
Mutations L/R
Epitope Location L6R
HXB2 Location L268R
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIIrGLNK had at least a 2-fold increase in relative enrichment, when cultured with 1 of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4762
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIItGLNK
Mutations L/T
Epitope Location L6T
HXB2 Location L268T
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIItGLNK had at least a 2-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4763
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLkK
Mutations N/K
Epitope Location N9K
HXB2 Location N271K
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLkK had at least a 2-fold to 5-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4764
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIvLGLNK
Mutations I/V
Epitope Location I5V
HXB2 Location I267V
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIvLGLNK had at least a 2-fold to 5-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4765
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILaLNK
Mutations G/A
Epitope Location G7A
HXB2 Location G269A
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILaLNK had at least a 2-fold to 5-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4766
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGvNK
Mutations L/V
Epitope Location L8V
HXB2 Location L270V
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGvNK had at least a 2-fold to 5-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4767
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGmNK
Mutations L/M
Epitope Location L8M
HXB2 Location L270M
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGmNK had at least a 2-fold to 5-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4768
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGwNK
Mutations L/W
Epitope Location L8W
HXB2 Location L270W
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGwNK had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4769
Epitope Seq.  KRWIILGLNK
Variant Seq.  KkWIILGLNK
Mutations R/K
Epitope Location R2K
HXB2 Location R264K
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KkWIILGLNK had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4770
Epitope Seq.  KRWIILGLNK
Variant Seq.  KcWIILGLNK
Mutations R/C
Epitope Location R2C
HXB2 Location R264C
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KcWIILGLNK had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4771
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWaILGLNK
Mutations I/A
Epitope Location I4A
HXB2 Location I266A
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWaILGLNK had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4772
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIlLGLNK
Mutations I/L
Epitope Location I5L
HXB2 Location I267L
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIlLGLNK had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4773
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIIfGLNK
Mutations L/F
Epitope Location L6F
HXB2 Location L268F
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIIfGLNK had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4774
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIIqGLNK
Mutations L/Q
Epitope Location L6Q
HXB2 Location L268Q
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIIqGLNK had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4775
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIIwGLNK
Mutations L/W
Epitope Location L6W
HXB2 Location L268W
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIIwGLNK had at least a 2-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4776
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLsK
Mutations N/S
Epitope Location N9S
HXB2 Location N271S
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLsK had at least a 2-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4777
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWItLGLNK
Mutations I/T
Epitope Location I5T
HXB2 Location I267T
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWItLGLNK had at least a 10-fold increase in relative enrichment, when cultured with 1 of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4778
Epitope Seq.  KRWIILGLNK
Variant Seq.  KwWIILGLNK
Mutations R/W
Epitope Location R2W
HXB2 Location R264W
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KwWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with 1 of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4779
Epitope Seq.  KRWIILGLNK
Variant Seq.  KgWIILGLNK
Mutations R/G
Epitope Location R2G
HXB2 Location R264G
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KgWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4780
Epitope Seq.  KRWIILGLNK
Variant Seq.  KtWIILGLNK
Mutations R/T
Epitope Location R2T
HXB2 Location R264T
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KtWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4781
Epitope Seq.  KRWIILGLNK
Variant Seq.  KsWIILGLNK
Mutations R/S
Epitope Location R2S
HXB2 Location R264S
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KsWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4782
Epitope Seq.  KRWIILGLNK
Variant Seq.  KaWIILGLNK
Mutations R/A
Epitope Location R2A
HXB2 Location R264A
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KaWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4783
Epitope Seq.  KRWIILGLNK
Variant Seq.  KqWIILGLNK
Mutations R/Q
Epitope Location R2Q
HXB2 Location R264Q
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KqWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4784
Epitope Seq.  KRWIILGLNK
Variant Seq.  KlWIILGLNK
Mutations R/L
Epitope Location R2L
HXB2 Location R264L
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KlWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with 1 of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.


Variant ID.  4785
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWImLGLNK
Mutations I/M
Epitope Location I5M
HXB2 Location I267M
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWImLGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4786
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIcLGLNK
Mutations I/C
Epitope Location I5C
HXB2 Location I267C
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIcLGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4787
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIIcGLNK
Mutations L/C
Epitope Location L6C
HXB2 Location L268C
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIIcGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4788
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIIsGLNK
Mutations L/S
Epitope Location L6S
HXB2 Location L268S
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIIsGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4789
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIIaGLNK
Mutations L/A
Epitope Location L6A
HXB2 Location L268A
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIIaGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4790
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIIsGLlK
Mutations L/S N/L
Epitope Location L6S N9L
HXB2 Location L268S N271L
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIIsGLlK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4791
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIIqGLaK
Mutations L/Q N/A
Epitope Location L6Q N9A
HXB2 Location L268Q N271A
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIIqGLaK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4792
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIInGLiK
Mutations L/N N/I
Epitope Location L6N N9I
HXB2 Location L268N N271I
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIInGLiK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4793
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLgK
Mutations N/G
Epitope Location N9G
HXB2 Location N271G
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLgK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4794
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLqK
Mutations N/Q
Epitope Location N9Q
HXB2 Location N271Q
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLqK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4795
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLhK
Mutations N/H
Epitope Location N9H
HXB2 Location N271H
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLhK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4796
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLtK
Mutations N/T
Epitope Location N9T
HXB2 Location N271T
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLtK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity without CTLs.


Variant ID.  4797
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWlILGLNK
Mutations I/L
Epitope Location I4L
HXB2 Location I266L
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWlILGLNK had at least a 10-fold increase in relative enrichment, when cultured with 1 of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4798
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWcILGLNK
Mutations I/C
Epitope Location I4C
HXB2 Location I266C
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWcILGLNK had at least a 2-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4799
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIsLGLNK
Mutations I/S
Epitope Location I5S
HXB2 Location I267S
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIsLGLNK had at least a 2-fold to 5-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4800
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWsILGLNK
Mutations I/S
Epitope Location I4S
HXB2 Location I266S
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWsILGLNK had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4801
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWrILGLNK
Mutations I/R
Epitope Location I4R
HXB2 Location I266R
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWrILGLNK had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4802
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRaIILGLNK
Mutations W/A
Epitope Location W3A
HXB2 Location W265A
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRaIILGLNK had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4803
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIgLGLNK
Mutations I/G
Epitope Location I5G
HXB2 Location I267G
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIgLGLNK had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4804
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIaLGLNK
Mutations I/A
Epitope Location I5A
HXB2 Location I267A
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIaLGLNK had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4805
Epitope Seq.  KRWIILGLNK
Variant Seq.  KeWIILGLNK
Mutations R/E
Epitope Location R2E
HXB2 Location R264E
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KeWIILGLNK had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4806
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLNt
Mutations K/T
Epitope Location K10T
HXB2 Location K272T
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNt had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4807
Epitope Seq.  KRWIILGLNK
Variant Seq.  hRWIILGLNK
Mutations K/H
Epitope Location K1H
HXB2 Location K263H
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, hRWIILGLNK had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4808
Epitope Seq.  KRWIILGLNK
Variant Seq.  vRWIILGLNK
Mutations K/V
Epitope Location K1V
HXB2 Location K263V
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, vRWIILGLNK had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4809
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILtLNK
Mutations G/T
Epitope Location G7T
HXB2 Location G269T
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILtLNK had at least a 5-fold to 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4810
Epitope Seq.  KRWIILGLNK
Variant Seq.  eRWIILGLNK
Mutations K/E
Epitope Location K1E
HXB2 Location K263E
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, eRWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4811
Epitope Seq.  KRWIILGLNK
Variant Seq.  fRWIILGLNK
Mutations K/F
Epitope Location K1F
HXB2 Location K263F
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, fRWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4812
Epitope Seq.  KRWIILGLNK
Variant Seq.  dRWIILGLNK
Mutations K/D
Epitope Location K1D
HXB2 Location K263D
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, dRWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4813
Epitope Seq.  KRWIILGLNK
Variant Seq.  sRWIILGLNK
Mutations K/S
Epitope Location K1S
HXB2 Location K263S
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, sRWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4814
Epitope Seq.  KRWIILGLNK
Variant Seq.  pRWIILGLNK
Mutations K/P
Epitope Location K1P
HXB2 Location K263P
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, pRWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4815
Epitope Seq.  KRWIILGLNK
Variant Seq.  wRWIILGLNK
Mutations K/W
Epitope Location K1W
HXB2 Location K263W
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, wRWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4816
Epitope Seq.  KRWIILGLNK
Variant Seq.  cRWIILGLNK
Mutations K/C
Epitope Location K1C
HXB2 Location K263C
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, cRWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4817
Epitope Seq.  KRWIILGLNK
Variant Seq.  lRWIILGLNK
Mutations K/L
Epitope Location K1L
HXB2 Location K263L
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, lRWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4818
Epitope Seq.  KRWIILGLNK
Variant Seq.  aRWIILGLNK
Mutations K/A
Epitope Location K1A
HXB2 Location K263A
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, aRWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4819
Epitope Seq.  KRWIILGLNK
Variant Seq.  sRWIILGLNK
Mutations K/S
Epitope Location K1S
HXB2 Location K263S
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, sRWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4820
Epitope Seq.  KRWIILGLNK
Variant Seq.  qRWIILGLNK
Mutations K/Q
Epitope Location K1Q
HXB2 Location K263Q
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, qRWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4821
Epitope Seq.  KRWIILGLNK
Variant Seq.  gRWIILGLNK
Mutations K/G
Epitope Location K1G
HXB2 Location K263G
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, gRWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4822
Epitope Seq.  KRWIILGLNK
Variant Seq.  mRWIILGLNK
Mutations K/M
Epitope Location K1M
HXB2 Location K263M
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, mRWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4823
Epitope Seq.  KRWIILGLNK
Variant Seq.  KpWIILGLNK
Mutations R/P
Epitope Location R2P
HXB2 Location R264P
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KpWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity without CTLs.


Variant ID.  4824
Epitope Seq.  KRWIILGLNK
Variant Seq.  KvWIILGLNK
Mutations R/V
Epitope Location R2V
HXB2 Location R264V
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KvWIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4825
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRvIILGLNK
Mutations W/V
Epitope Location W3V
HXB2 Location W265V
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRvIILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4826
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWpILGLNK
Mutations I/P
Epitope Location I4P
HXB2 Location I266P
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWpILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4827
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWwILGLNK
Mutations I/W
Epitope Location I4W
HXB2 Location I266W
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWwILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4828
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWgILGLNK
Mutations I/G
Epitope Location I4G
HXB2 Location I266G
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWgILGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4829
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIrLGLNK
Mutations I/R
Epitope Location I5R
HXB2 Location I267R
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIrLGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4830
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIIkGLNK
Mutations L/K
Epitope Location L6K
HXB2 Location L268K
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIIkGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity without CTLs.


Variant ID.  4831
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLNe
Mutations K/E
Epitope Location K10E
HXB2 Location K272E
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNe had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity without CTLs.


Variant ID.  4832
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIIeGLNK
Mutations L/E
Epitope Location L6E
HXB2 Location L268E
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIIeGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4833
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIIgGLNK
Mutations L/G
Epitope Location L6G
HXB2 Location L268G
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIIgGLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4834
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILlLNK
Mutations G/L
Epitope Location G7L
HXB2 Location G269L
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILlLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4835
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILsLNK
Mutations G/S
Epitope Location G7S
HXB2 Location G269S
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILsLNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4836
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGtNK
Mutations L/T
Epitope Location L8T
HXB2 Location L270T
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGtNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4837
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGeNK
Mutations L/E
Epitope Location L8E
HXB2 Location L270E
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGeNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4838
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGgNK
Mutations L/G
Epitope Location L8G
HXB2 Location L270G
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGgNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4839
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGaNK
Mutations L/A
Epitope Location L8A
HXB2 Location L270A
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGaNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4840
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGrNK
Mutations L/R
Epitope Location L8R
HXB2 Location L270R
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGrNK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4841
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLpK
Mutations N/P
Epitope Location N9P
HXB2 Location N271P
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLpK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4842
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLwK
Mutations N/W
Epitope Location N9W
HXB2 Location N271W
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLwK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4843
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLvK
Mutations N/V
Epitope Location N9V
HXB2 Location N271V
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLvK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4844
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLaK
Mutations N/A
Epitope Location N9A
HXB2 Location N271A
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLaK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4845
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLlK
Mutations N/L
Epitope Location N9L
HXB2 Location N271L
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLlK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4846
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLrK
Mutations N/R
Epitope Location N9R
HXB2 Location N271R
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLrK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4847
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLNm
Mutations K/M
Epitope Location K10M
HXB2 Location K272M
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNm had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4848
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLNv
Mutations K/V
Epitope Location K10V
HXB2 Location K272V
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNv had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4849
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLNp
Mutations K/P
Epitope Location K10P
HXB2 Location K272P
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNp had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4850
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLNl
Mutations K/L
Epitope Location K10L
HXB2 Location K272L
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNl had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4851
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLNq
Mutations K/Q
Epitope Location K10Q
HXB2 Location K272Q
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNq had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4852
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLNw
Mutations K/W
Epitope Location K10W
HXB2 Location K272W
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNw had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4853
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLNg
Mutations K/G
Epitope Location K10G
HXB2 Location K272G
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLNg had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a substantially decreased replicative capacity.


Variant ID.  4856
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIILGLmK
Mutations I/K
Epitope Location I+1K
HXB2 Location I273K
Mutation Type
Epitope Subtype B
Variant Subtype B
Method Other, Relative replication capacity assay
Note Relative to consensus variant, KRWIILGLmK had at least a 10-fold increase in relative enrichment, when cultured with each of 2 KRWIILGLNK-specific CTL clones, vs. without CTLs, but also had a decreased replicative capacity.

References

Gorin2017 Aleksandr M. Gorin, Yushen Du, Franklin Y. Liu, Tian-Hao Zhang, Hwee L. Ng, Christian Hofmann, William G. Cumberland, Ren Sun, and Otto O. Yang. HIV-1 Epitopes Presented by MHC Class I Types Associated with Superior Immune Containment of Viremia Have Highly Constrained Fitness Landscapes. PLoS Pathog, 13(8):e1006541, Aug 2017. PubMed ID: 28787455. Show all entries for this paper.


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