HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 62532

HXB2 Location  Nef(194-202)   Nef Epitope Map
View variants at this location
Epitope MARELHPEY   Epitope Alignment
vARELHPEY   observed variant
Epitope Name Nef-MY9
Species (MHC/HLA human(C*12:02)

Variant Details

Showing all: 1 variant(s).

Variant ID.  4492
Epitope Seq.  MARELHPEY
Variant Seq.  vARELHPEY
Mutations M/V
Epitope Location M1V
HXB2 Location M194V
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Other
Note vARELHPEY was observed in HLA-peptide complexes from C*12:02-expressing cells infected with NL4-3 and corresponding clade B consensus epitope MARELHPEY has been previously reported as immunodominant. [Chikata2017, PMID: 28968792]


Chikata2019 Takayuki Chikata, Wayne Paes, Tomohiro Akahoshi, Thomas Partridge, Hayato Murakoshi, Hiroyuki Gatanaga, Nicola Ternette, Shinichi Oka, Persephone Borrow, and Masafumi Takiguchi. Identification of Immunodominant HIV-1 Epitopes Presented by HLA-C*12:02, a Protective Allele, Using an Immunopeptidomics Approach. J. Virol., 93(17), 1 Sep 2019. PubMed ID: 31217245. Show all entries for this paper.

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