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HIV Molecular Immunology Database

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Found 1 matching record:

Displaying record number 62529

HXB2 Location  Nef(82-90)   Nef Epitope Map
View variants at this location
Epitope KGALDLSHF   Epitope Alignment
Variants
KaAvDLSHF   observed variant
Epitope Name Nef-KF9
Species (MHC/HLA human(C*12:02)

Variant Details

Showing all: 1 variant(s).


Variant ID.  4490
Epitope Seq.  KGALDLSHF
Variant Seq.  KaAvDLSHF
Mutations G/A L/V
Epitope Location G2A L4V
HXB2 Location G83A L85V
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Other
Note KaAvDLSHF was observed in HLA-peptide complexes from C*12:02-expressing cells infected with NL4-3 and corresponds to clade B consensus sequence KGALDLSHF.

References

Chikata2019 Takayuki Chikata, Wayne Paes, Tomohiro Akahoshi, Thomas Partridge, Hayato Murakoshi, Hiroyuki Gatanaga, Nicola Ternette, Shinichi Oka, Persephone Borrow, and Masafumi Takiguchi. Identification of Immunodominant HIV-1 Epitopes Presented by HLA-C*12:02, a Protective Allele, Using an Immunopeptidomics Approach. J. Virol., 93(17), 1 Sep 2019. PubMed ID: 31217245. Show all entries for this paper.


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