HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(369-377) | Gag Epitope Map
View variants at this location |
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| Epitope |
QVQHTNIMM
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Epitope Alignment | ||||||||||
| Variants |
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| Species (MHC/HLA) | human(B*07:02) | |||||||||||
Showing all: 3 variant(s).
| Variant ID. | 4156 |
|---|---|
| Epitope Seq. | QVQHTNIMM |
| Variant Seq. | QaQqpNVMM |
| Mutations | V/A H/Q T/P I/V |
| Epitope Location | V2A H4Q T5P I7V |
| HXB2 Location | V370A H372Q T373P I375V |
| Mutation Type | SF: susceptible form |
| Epitope Subtype | A, D |
| Variant Subtype | A, D |
| Method | CD8 T-cell Elispot - IFNy, Other, Tetramer binding |
| Note | 5/8 female B*7202+ patients responded to this novel variant of QVQHTNIMM, QaQqpNVMM, with a mean of 96 SFU/million cells. |
| Variant ID. | 4157 |
|---|---|
| Epitope Seq. | QVQHTNIMM |
| Variant Seq. | QanantaIM |
| Mutations | V/A Q/N H/A T/N N/T I/A M/I |
| Epitope Location | V2A Q3N H4A T5N N6T I7A M8I |
| HXB2 Location | V370A Q371N H372A T373N N374T I375A M376I |
| Mutation Type | SF: susceptible form |
| Epitope Subtype | A, D |
| Variant Subtype | A, D |
| Method | CD8 T-cell Elispot - IFNy, Other, Tetramer binding |
| Note | 6/8 female B*7202+ patients responded to this novel variant of QVQHTNIMM, QanantaIM, with a mean of 109 SFU/million cells. |
| Variant ID. | 4158 |
|---|---|
| Epitope Seq. | QVQHTNIMM |
| Variant Seq. | QVngntaiM |
| Mutations | Q/N H/G T/N N/T I/A M/I |
| Epitope Location | Q3N H4G T5N N6T I7A M8I |
| HXB2 Location | Q371N H372G T373N N374T I375A M376I |
| Mutation Type | SF: susceptible form |
| Epitope Subtype | A, D |
| Variant Subtype | A, D |
| Method | CD8 T-cell Elispot - IFNy, Other, Tetramer binding |
| Note | 6/8 female B*7202+ patients responded to this novel variant of QVQHTNIMM, QVngntaiM, with a mean of 99 SFU/million cells. |
Luo2012 Ma Luo, Christina A. Daniuk, Tamsir O. Diallo, Rupert E. Capina, Joshua Kimani, Charles Wachihi, Makubo Kimani, Thomas Bielawny, Trevor Peterson, Mark G. R. Mendoza, Sandra Kiazyk, T. Blake Ball, and Francis A. Plummer. For Protection from HIV-1 Infection, More Might Not Be Better: A Systematic Analysis of HIV Gag Epitopes of Two Alleles Associated with Different Outcomes of HIV-1 Infection. J. Virol., 86(2):1166-1180, Jan 2012. PubMed ID: 22072744. Show all entries for this paper.