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Found 1 matching record:

Displaying record number 61974

HXB2 Location  Gag(242-250)   Gag Epitope Map
View variants at this location
Epitope TPQEQIGWM   Epitope Alignment
Variants
TPQEQlGWM   non-susceptible form
Species (MHC/HLA human(B*07:02)

Variant Details

Showing all: 1 variant(s).


Variant ID.  4155
Epitope Seq.  TPQEQIGWM
Variant Seq.  TPQEQlGWM
Mutations I/L
Epitope Location I6L
HXB2 Location I247L
Mutation Type NSF: non-susceptible form
Epitope Subtype A, D
Variant Subtype A, D
Method Other, Tetramer binding
Note Variant TPQEQlGWM of epitope TPQEQIGWM was a novel epitope based on binding studies and iTope epitope discovery system. It did not bind any of the tested B*0702 subjects, though not all subjects were tested.

References

Luo2012 Ma Luo, Christina A. Daniuk, Tamsir O. Diallo, Rupert E. Capina, Joshua Kimani, Charles Wachihi, Makubo Kimani, Thomas Bielawny, Trevor Peterson, Mark G. R. Mendoza, Sandra Kiazyk, T. Blake Ball, and Francis A. Plummer. For Protection from HIV-1 Infection, More Might Not Be Better: A Systematic Analysis of HIV Gag Epitopes of Two Alleles Associated with Different Outcomes of HIV-1 Infection. J. Virol., 86(2):1166-1180, Jan 2012. PubMed ID: 22072744. Show all entries for this paper.


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