HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 61967

HXB2 Location  Gag(355-363)   Gag Epitope Map
View variants at this location
Epitope GPGHKARVL   Epitope Alignment
GPsHKARVL   susceptible form
Species (MHC/HLA human(B*07:02)

Variant Details

Showing all: 1 variant(s).

Variant ID.  4154
Epitope Seq.  GPGHKARVL
Variant Seq.  GPsHKARVL
Mutations G/S
Epitope Location G3S
HXB2 Location G357S
Mutation Type SF: susceptible form
Epitope Subtype A, D
Variant Subtype A, D
Method CD8 T-cell Elispot - IFNy, Other, Tetramer binding
Note 9/16 female B*0702+ patients responded to this previously known variant of GPGHKARVL, GPsHKARVL, with a mean of 84 SFU/million cells.


Luo2012 Ma Luo, Christina A. Daniuk, Tamsir O. Diallo, Rupert E. Capina, Joshua Kimani, Charles Wachihi, Makubo Kimani, Thomas Bielawny, Trevor Peterson, Mark G. R. Mendoza, Sandra Kiazyk, T. Blake Ball, and Francis A. Plummer. For Protection from HIV-1 Infection, More Might Not Be Better: A Systematic Analysis of HIV Gag Epitopes of Two Alleles Associated with Different Outcomes of HIV-1 Infection. J. Virol., 86(2):1166-1180, Jan 2012. PubMed ID: 22072744. Show all entries for this paper.

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