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Found 1 matching record:

Displaying record number 61855

HXB2 Location  Pol(496-504)   Pol Epitope Map
View variants at this location
Epitope IYQEPFKNL   Epitope Alignment
Variants
IYQdPFKNL   observed variant
Epitope Name IL9
Species (MHC/HLA human(A*24:02)

Variant Details

Showing all: 1 variant(s).


Variant ID.  4084
Epitope Seq.  IYQEPFKNL
Variant Seq.  IYQdPFKNL
Mutations E/D
Epitope Location E4D
HXB2 Location E499D
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Intracellular cytokine staining, Other
Note 20.8% (60/289) chronically HIV-1-infected Japanese patients carried the mutant, IL9-4D, IYQdPFKNL. IL9-specific CTL and CTL lines were able to cross-recognize this variant.

References

Zou2019 Chengcheng Zou, Hayato Murakoshi, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomáš Hanke, and Masafumi Takiguchi. Effective Suppression of HIV-1 Replication by Cytotoxic T Lymphocytes Specific for Pol Epitopes in Conserved Mosaic Vaccine Immunogens. J. Virol., 93(7), 1 Apr 2019. PubMed ID: 30674626. Show all entries for this paper.


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