HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Pol(496-504) | Pol Epitope Map
View variants at this location |
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|---|---|---|---|---|---|---|
| Epitope |
IYQEPFKNL
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Epitope Alignment | ||||
| Variants |
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| Epitope Name | IL9 | |||||
| Species (MHC/HLA) | human(A*24:02) | |||||
Showing all: 1 variant(s).
| Variant ID. | 4084 |
|---|---|
| Epitope Seq. | IYQEPFKNL |
| Variant Seq. | IYQdPFKNL |
| Mutations | E/D |
| Epitope Location | E4D |
| HXB2 Location | E499D |
| Mutation Type | OV: observed variant |
| Epitope Subtype | B |
| Variant Subtype | B |
| Method | Intracellular cytokine staining, Other |
| Note | 20.8% (60/289) chronically HIV-1-infected Japanese patients carried the mutant, IL9-4D, IYQdPFKNL. IL9-specific CTL and CTL lines were able to cross-recognize this variant. |
Zou2019 Chengcheng Zou, Hayato Murakoshi, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomáš Hanke, and Masafumi Takiguchi. Effective Suppression of HIV-1 Replication by Cytotoxic T Lymphocytes Specific for Pol Epitopes in Conserved Mosaic Vaccine Immunogens. J. Virol., 93(7), 1 Apr 2019. PubMed ID: 30674626. Show all entries for this paper.