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Displaying record number 61605

HXB2 Location  Gag(71-79)   Gag Epitope Map
View variants at this location
Epitope GSEELRSLY   Epitope Alignment
Variants
GSEELkSLY   escape documented in this paper; observed variant
GSaELRSLY   escape documented in this paper; observed variant
GSEELRSLf   escape documented in this paper; observed variant
Epitope Name A01-GY9 Gag
Species (MHC/HLA human(A*01)

Variant Details

Showing all: 3 variant(s).


Variant ID.  3973
Epitope Seq.  GSEELRSLY
Variant Seq.  GSEELkSLY
Mutations R/K
Epitope Location R6K
HXB2 Location R76K
Mutation Type E: escape documented in this paper
OV: observed variant
Method Other
Note Variant GSEELkSLY, R6K, was found in Subject 9213 haplotypes at varying frequencies on days 0 and 165 only, not detected at intervening time points of days 3 and 59 and lost at later time points than d165.


Variant ID.  3974
Epitope Seq.  GSEELRSLY
Variant Seq.  GSaELRSLY
Mutations E/A
Epitope Location E3A
HXB2 Location E73A
Mutation Type E: escape documented in this paper
OV: observed variant
Method Other
Note Variant GSaELRSLY, E3A, was found in a Subject 9213 haplotype only on day 59, lost at later time points.


Variant ID.  3975
Epitope Seq.  GSEELRSLY
Variant Seq.  GSEELRSLf
Mutations Y/F
Epitope Location Y9F
HXB2 Location Y79F
Mutation Type E: escape documented in this paper
OV: observed variant
Method Other
Note Variant GSEELRSLY, Y9F, was found in Subject 9213 haplotypes at varying frequencies on day 1543 only. This escape is at an anchor residue.

References

Pandit2014 Aridaman Pandit and Rob J. de Boer. Reliable Reconstruction of HIV-1 Whole Genome Haplotypes Reveals Clonal Interference and Genetic Hitchhiking among Immune Escape Variants. Retrovirology, 11:56, 4 Jul 2014. PubMed ID: 24996694. Show all entries for this paper.


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