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Displaying record number 61605

HXB2 Location Gag(71-79) Gag Epitope Map
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GSEELRSLY

`GSEELkSLY`		escape documented in this paper; observed variant
`GSaELRSLY`		escape documented in this paper; observed variant
`GSEELRSLf`		escape documented in this paper; observed variant

Epitope Name A01-GY9 Gag

Species (MHC/HLA) human(A*01)

Variant Details

Showing all: 3 variant(s).

Variant ID.	`3973`
Epitope Seq.	`GSEELRSLY`
Variant Seq.	`GSEELkSLY`
Mutations	R/K
Epitope Location	R6K
HXB2 Location	R76K
Mutation Type	E: escape documented in this paper OV: observed variant
Method	Other
Note	Variant GSEELkSLY, R6K, was found in Subject 9213 haplotypes at varying frequencies on days 0 and 165 only, not detected at intervening time points of days 3 and 59 and lost at later time points than d165.

Variant ID.	`3974`
Epitope Seq.	`GSEELRSLY`
Variant Seq.	`GSaELRSLY`
Mutations	E/A
Epitope Location	E3A
HXB2 Location	E73A
Mutation Type	E: escape documented in this paper OV: observed variant
Method	Other
Note	Variant GSaELRSLY, E3A, was found in a Subject 9213 haplotype only on day 59, lost at later time points.

Variant ID.	`3975`
Epitope Seq.	`GSEELRSLY`
Variant Seq.	`GSEELRSLf`
Mutations	Y/F
Epitope Location	Y9F
HXB2 Location	Y79F
Mutation Type	E: escape documented in this paper OV: observed variant
Method	Other
Note	Variant GSEELRSLY, Y9F, was found in Subject 9213 haplotypes at varying frequencies on day 1543 only. This escape is at an anchor residue.

References

Pandit2014 Aridaman Pandit and Rob J. de Boer. Reliable Reconstruction of HIV-1 Whole Genome Haplotypes Reveals Clonal Interference and Genetic Hitchhiking among Immune Escape Variants. Retrovirology, 11:56, 4 Jul 2014. PubMed ID: 24996694. Show all entries for this paper.