HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 61540

HXB2 Location  Gag(277-285)   Gag Epitope Map
View variants at this location
Epitope YSPTSILDI   Epitope Alignment
YSPvSILDI   subtype-specific susceptible form
Epitope Name Gag YI9
Species (MHC/HLA human(C*01:02)

Variant Details

Showing all: 1 variant(s).

Variant ID.  3942
Epitope Seq.  YSPTSILDI
Variant Seq.  YSPvSILDI
Mutations T/V
Epitope Location T4V
HXB2 Location T280V
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype CRF01_AE
Method CD8 T-cell Elispot - IFNy, Intracellular cytokine staining, Sequence
Note A/E clade epitope YSPvSILDI was found in 15/26 A/E patients of the KI cohort, though it was found in 345/1644 B virus and 212/315 clade A/E virus sequences in the Los Alamos HIV-1 database. It was recognized by CTL from clade A/E-infected patient KI-724 which had been elicited by consensus clade B YI9.


Watanabe2013 Koji Watanabe, Hayato Murakoshi, Yoshiko Tamura, Madoka Koyanagi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Identification of Cross-Clade CTL Epitopes in HIV-1 Clade A/E-Infected Individuals by Using the Clade B Overlapping Peptides. Microbes Infect., 15(13):874-886, Nov 2013. PubMed ID: 23968885. Show all entries for this paper.

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