HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Pol(783-791) | Pol Epitope Map
View variants at this location |
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|---|---|---|---|---|---|---|
| Epitope |
LEGKIILVA
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Epitope Alignment | ||||
| Variants |
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| Epitope Name | PolLA9 | |||||
| Species (MHC/HLA) | human(B*40:06) | |||||
Showing all: 1 variant(s).
| Variant ID. | 3917 |
|---|---|
| Epitope Seq. | LEGKIILVA |
| Variant Seq. | LEGKvILVA |
| Mutations | I/V |
| Epitope Location | I5V |
| HXB2 Location | I787V |
| Mutation Type | OV: observed variant |
| Epitope Subtype | B |
| Variant Subtype | B |
| Method | Sequence |
| Note | Pol LEGKIILVA variant, LEGKvILVA (5V) was seen at 35.6% in sequences from the Los Alamos database, but at 15.3% in this Japanese cohort. LA9-5V and LA9 were cross-recognized in 3/4 HLA-A*0206 subjects - KI-763, KI-912, KI-928 and KI-756. |
Murakoshi2015 Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Takuya Naruto, Rie Maruyama, Yoshiko Tamura, Naoki Ishizuka, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Clinical Control of HIV-1 by Cytotoxic T Cells Specific for Multiple Conserved Epitopes. J. Virol., 89(10):5330-5339, May 2015. PubMed ID: 25741000. Show all entries for this paper.