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Displaying record number 61469

HXB2 Location Gag(277-285) Gag Epitope Map
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Epitope

YSPVSILDI

Epitope Alignment

Variants

YSPtSILDI escape documented in this paper

Epitope Name YI9

Species (MHC/HLA) human(C*01:02)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`3905`
Epitope Seq.	`YSPVSILDI`
Variant Seq.	`YSPtSILDI`
Mutations	V/T
Epitope Location	V4T
HXB2 Location	V280T
Mutation Type	E: escape documented in this paper
Epitope Subtype	CRF01_AE
Variant Subtype	CRF01_AE
Method	CD8 T-cell Elispot - IFNy, Intracellular cytokine staining, Other, Sequence
Note	Mutant YSPtSILDI, was confirmed as an escape by EliSpot in two HLA-Cw*0102 positive patients as well as YI9-specific T cells.

References

VanTran2016 Giang Van Tran, Takayuki Chikata, Jonathan M. Carlson, Hayato Murakoshi, Dung Hoai Nguyen, Yoshiko Tamura, Tomohiro Akahoshi, Nozomi Kuse, Keiko Sakai, Sachiko Sakai, Kyle Cobarrubias, Shinichi Oka, Zabrina L. Brumme, Kinh Van Nguyen, Masafumi Takiguchi, and NHTD Treatment-Naive Cohort Study Group. A Strong Association of Human Leukocyte Antigen-Associated Pol and Gag Mutations with Clinical Parameters in HIV-1 Subtype A/E Infection. AIDS, 30(5):681-689, 13 Mar 2016. PubMed ID: 26595539. Show all entries for this paper.