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Displaying record number 61456

HXB2 Location  Nef(174-184)   Nef Epitope Map
View variants at this location
Epitope EDPEKEVLEWR   Epitope Alignment
Variants
dDPEKEVLvWk   observed variant
gDPErEVLqWR   observed variant
dDPErEiLvWk   observed variant
dDPErEVLqWR   observed variant
dDPErEVLvWk   observed variant
dDPEKEVLqWR   observed variant
dDPErEVLmWk   observed variant
dDtEKEVLvWk   observed variant
eDPErEVLqWk   observed variant
eDPErEVLqWR   observed variant
dDPEgEVLqWR   observed variant
dDPdgEVLqWR   observed variant
EDtEKEVLvWk   observed variant
dDlErEVLmWk   observed variant
EDPEgEVLqWk   observed variant
dDPEKEVLqWk   observed variant
Epitope Name Nef174-184
Species (MHC/HLA human

Variant Details

Showing all: 16 variant(s).


Variant ID.  3858
Epitope Seq.  EDPEKEVLEWR
Variant Seq.  dDPEKEVLvWk
Mutations E/D E/V
Epitope Location E1D E9V
HXB2 Location E174D E182V
Mutation Type OV: observed variant
Method Other, Sequence
Note Epitope dDPEKEVLvWK of epitope Nef174-184 was the circulating autologous form in acute patient 502-0341 of the STEP trial, as 2/7 HIV-1 sequences. The patient also carried variant forms dDPErEVLvWK and dDPErEiLvWK.


Variant ID.  3859
Epitope Seq.  EDPEKEVLEWR
Variant Seq.  gDPErEVLqWR
Mutations E/G K/R E/Q
Epitope Location E1G K5R E9Q
HXB2 Location E174G K178R E182Q
Mutation Type OV: observed variant
Method Other, Sequence
Note Variant gDPErEVLqWR of epitope Nef174-184 was seen circulating in acute patient 502-0648 of the STEP trial, in 1/4 HIV-1 sequences. The autologous sequence in this patient was dDPErEVLqWR.


Variant ID.  3860
Epitope Seq.  EDPEKEVLEWR
Variant Seq.  dDPErEiLvWk
Mutations E/D R/K K/R V/I E/V
Epitope Location E1D R11K K5R V7I E9V
HXB2 Location E174D R184K K178R V180I E182V
Mutation Type OV: observed variant
Method Other, Sequence
Note Variant dDPErEiLvWk of epitope Nef174-184 was seen circulating in acute patient 502-0341 of the STEP trial, in 1/7 HIV-1 sequences. The autologous sequence in this patient was dDPEKEVLvWk. Another variant in this patient was dDPErEVLvWk.


Variant ID.  3861
Epitope Seq.  EDPEKEVLEWR
Variant Seq.  dDPErEVLqWR
Mutations E/D K/R E/Q
Epitope Location E1D K5R E9Q
HXB2 Location E174D K178R E182Q
Mutation Type OV: observed variant
Method Other, Sequence
Note Epitope dDPErEVLqWR of epitope Nef174-184 was the circulating autologous form in acute patients 502-0648 and 502-0841 of the STEP trial, as 3/4 and 1/4 HIV-1 sequences. The patients also carried other variant forms - gDPErEVLqWR; and eDPErEVLqWR, dDPEgEVLqWR and dDPdgEVLqWR.


Variant ID.  3862
Epitope Seq.  EDPEKEVLEWR
Variant Seq.  dDPErEVLvWk
Mutations E/D R/K K/R E/V
Epitope Location E1D R11K K5R E9V
HXB2 Location E174D R184K K178R E182V
Mutation Type OV: observed variant
Method Other, Sequence
Note Variant dDPErEVLvWk of epitope Nef174-184 was seen circulating in acute patient 502-0341 of the STEP trial, in 4/7 HIV-1 sequences. The autologous sequence in this patient was dDPEKEVLvWk. Another variant in this patient was dDPErEiLvWk.


Variant ID.  3863
Epitope Seq.  EDPEKEVLEWR
Variant Seq.  dDPEKEVLqWR
Mutations E/D E/Q
Epitope Location E1D E9Q
HXB2 Location E174D E182Q
Mutation Type OV: observed variant
Method Other, Sequence
Note Epitope dDPEkEVLqWR of epitope Nef174-184 was the circulating autologous form in acute patient 502-0879 of the STEP trial, as 3/5 HIV-1 sequences. The patients also carried another variant form - dDPEkEVLqWk.


Variant ID.  3864
Epitope Seq.  EDPEKEVLEWR
Variant Seq.  dDPErEVLmWk
Mutations E/D R/K K/R E/M
Epitope Location E1D R11K K5R E9M
HXB2 Location E174D R184K K178R E182M
Mutation Type OV: observed variant
Method Other, Sequence
Note Epitope dDPErEVLmWk of epitope Nef174-184 was the circulating autologous form in acute patient 502-0897 of the STEP trial, as 9/10 HIV-1 sequences. The patients also carried another variant form - dDlErEVLmWk.


Variant ID.  3865
Epitope Seq.  EDPEKEVLEWR
Variant Seq.  dDtEKEVLvWk
Mutations E/D E/V
Epitope Location E1D E9V
HXB2 Location E174D E182V
Mutation Type OV: observed variant
Method Other, Sequence
Note Epitope dDtEKEVLvWk of epitope Nef174-184 was the circulating autologous form in acute patient 502-1512 of the STEP trial, as 7/11 HIV-1 sequences. The patient also carried variant forms eDtEKEVLvWk.


Variant ID.  3866
Epitope Seq.  EDPEKEVLEWR
Variant Seq.  eDPErEVLqWk
Mutations E/D E/V
Epitope Location E1D E9V
HXB2 Location E174D E182V
Mutation Type OV: observed variant
Method Other, Sequence
Note Epitope eDPErEVLqWk of epitope Nef174-184 was the circulating autologous form in acute patient 502-2586 of the STEP trial, as 5/6 HIV-1 sequences. The patient also carried variant forms eDPEgEVLqWk.


Variant ID.  3867
Epitope Seq.  EDPEKEVLEWR
Variant Seq.  eDPErEVLqWR
Mutations K/R E/Q
Epitope Location K5R E9Q
HXB2 Location K178R E182Q
Mutation Type OV: observed variant
Method Other, Sequence
Note Variant EDPErEVLqWR of epitope Nef174-184 was seen circulating in acute patient 502-0841 of the STEP trial, in 1/4 HIV-1 sequences. The autologous sequence in this patient was dDPErEVLqWR. Other variants in this patient were dDPEgEVLqWR and dDPdgEVLqWR.


Variant ID.  3868
Epitope Seq.  EDPEKEVLEWR
Variant Seq.  dDPEgEVLqWR
Mutations E/D K/G E/Q
Epitope Location E1D K5G E9Q
HXB2 Location E174D K178G E182Q
Mutation Type OV: observed variant
Method Other, Sequence
Note Variant dDPEgEVLqWR of epitope Nef174-184 was seen circulating in acute patient 502-0841 of the STEP trial, in 1/4 HIV-1 sequences. The autologous sequence in this patient was dDPErEVLqWR. Other variants in this patient were EDPErEVLqWR and dDPdgEVLqWR.


Variant ID.  3869
Epitope Seq.  EDPEKEVLEWR
Variant Seq.  dDPdgEVLqWR
Mutations E/D E/D K/G E/Q
Epitope Location E1D E4D K5G E9Q
HXB2 Location E174D E177D K178G E182Q
Mutation Type OV: observed variant
Method Other, Sequence
Note Variant dDPdgEVLqWR of epitope Nef174-184 was seen circulating in acute patient 502-0841 of the STEP trial, in 1/4 HIV-1 sequences. The autologous sequence in this patient was dDPErEVLqWR. Other variants in this patient were EDPErEVLqWR and dDPEgEVLqWR.


Variant ID.  3870
Epitope Seq.  EDPEKEVLEWR
Variant Seq.  EDtEKEVLvWk
Mutations R/K P/T E/V
Epitope Location R11K P3T E9V
HXB2 Location R184K P176T E182V
Mutation Type OV: observed variant
Method Other, Sequence
Note Variant EDtEKEVLvWk of epitope Nef174-184 was seen circulating in acute patient 502-1512 of the STEP trial, in 4/11 HIV-1 sequences. The autologous sequence in this patient was dDtEKEVLvWk.


Variant ID.  3871
Epitope Seq.  EDPEKEVLEWR
Variant Seq.  dDlErEVLmWk
Mutations E/D R/K P/L K/R E/M
Epitope Location E1D R11K P3L K5R E9M
HXB2 Location E174D R184K P176L K178R E182M
Mutation Type OV: observed variant
Method Other, Sequence
Note Variant dDlErEVLmWk of epitope Nef174-184 was seen circulating in acute patient 502-0897 of the STEP trial, in 1/10 HIV-1 sequences. The autologous sequence in this patient was dDPErEVLmWk.


Variant ID.  3872
Epitope Seq.  EDPEKEVLEWR
Variant Seq.  EDPEgEVLqWk
Mutations R/K K/G E/Q
Epitope Location R11K K5G E9Q
HXB2 Location R184K K178G E182Q
Mutation Type OV: observed variant
Method Other, Sequence
Note Variant EDPEgEVLqWk of epitope Nef174-184 was seen circulating in acute patient 502-2586 of the STEP trial, in 1/6 HIV-1 sequences. The autologous sequence in this patient was EDPErEVLqWk.


Variant ID.  3873
Epitope Seq.  EDPEKEVLEWR
Variant Seq.  dDPEKEVLqWk
Mutations E/D R/K E/Q
Epitope Location E1D R11K E9Q
HXB2 Location E174D R184K E182Q
Mutation Type OV: observed variant
Method Other, Sequence
Note Variant dDPEKEVLqWk of epitope Nef174-184 was seen circulating in acute patient 502-0879 of the STEP trial, in 2/5 HIV-1 sequences. The autologous sequence in this patient was dDPEKEVLqWR.

References

Park2016a Sung Yong Park, Wendy J Mack, and Ha Y Lee. Enhancement of viral escape in HIV-1 Nef by STEP vaccination. AIDS, 30(16):2449-2458, Oct 23 2016. PubMed ID: 27427874. Show all entries for this paper.


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