HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 61259

HXB2 Location  Pol(101-110)   Pol Epitope Map
View variants at this location
Epitope KMIGGVGGFI   Epitope Alignment
KMIGGiGGFI   drug induced; observed variant
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).

Variant ID.  3783
Epitope Seq.  KMIGGVGGFI
Variant Seq.  KMIGGiGGFI
Mutations V/I
Epitope Location V6I
HXB2 Location V106I
Mutation Type DI: drug induced
OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Other, Sequence
Note The drug induced mutation I50V is seen in several ART-naive patients as epitope KMIGGVGGFI. 11/49 subjects responded to this variant.


Blanco-Heredia2016 Juan Blanco-Heredia, Aarón Lecanda, Humberto Valenzuela-Ponce, Christian Brander, Santiago Ávila-Rios, and Gustavo Reyes-Terán. Identification of Immunogenic Cytotoxic T Lymphocyte Epitopes Containing Drug Resistance Mutations in Antiretroviral Treatment-Naive HIV-Infected Individuals. PLoS One, 11(1):e0147571, 2016. PubMed ID: 26808823. Show all entries for this paper.

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