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Found 1 matching record:

Displaying record number 61250

HXB2 Location  Pol(283-290)   Pol Epitope Map
View variants at this location
Epitope TAFTIPSI   Epitope Alignment
Variants
TAFTIPSt   escape documented in this paper
Epitope Name TI8
Species (MHC/HLA human(B*51)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3774
Epitope Seq.  TAFTIPSI
Variant Seq.  TAFTIPSt
Mutations I/T
Epitope Location I8T
HXB2 Location I290T
Mutation Type E: escape documented in this paper
Epitope Subtype B, CRF01_AE
Variant Subtype B, CRF01_AE
Method Other
Note Escape variant TAFTIPSt was seen in all 7 patients by 6-months post-seroconversion. Mutation rate increased from 2.86% to 14.13% to 54.49% by 6 months of HIV-1 infection.

References

Sun2016a Jianping Sun, Yan Zhao, Yanchun Peng, Zhen Han, Guihai Liu, Ling Qin, Sai Liu, Huanhuan Sun, Hao Wu, Tao Dong, and Yonghong Zhang. Multiple T-Cell Responses Are Associated with Better Control of Acute HIV-1 Infection: An Observational Study. Medicine, 95(30):e4429, Jul 2016. PubMed ID: 27472741. Show all entries for this paper.


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