Search the Epitope Variant and Escape Mutation Database

Help

Found 1 matching record:

Displaying record number 61250

HXB2 Location Pol(283-290) Pol Epitope Map
View variants at this location

Epitope

TAFTIPSI

Epitope Alignment

Variants

TAFTIPSt escape documented in this paper

Epitope Name TI8

Species (MHC/HLA) human(B*51)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`3774`
Epitope Seq.	`TAFTIPSI`
Variant Seq.	`TAFTIPSt`
Mutations	I/T
Epitope Location	I8T
HXB2 Location	I290T
Mutation Type	E: escape documented in this paper
Epitope Subtype	B, CRF01_AE
Variant Subtype	B, CRF01_AE
Method	Other
Note	Escape variant TAFTIPSt was seen in all 7 patients by 6-months post-seroconversion. Mutation rate increased from 2.86% to 14.13% to 54.49% by 6 months of HIV-1 infection.

References

Sun2016a Jianping Sun, Yan Zhao, Yanchun Peng, Zhen Han, Guihai Liu, Ling Qin, Sai Liu, Huanhuan Sun, Hao Wu, Tao Dong, and Yonghong Zhang. Multiple T-Cell Responses Are Associated with Better Control of Acute HIV-1 Infection: An Observational Study. Medicine, 95(30):e4429, Jul 2016. PubMed ID: 27472741. Show all entries for this paper.