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Found 1 matching record:

Displaying record number 61223

HXB2 Location  Gag(140-147)   Gag Epitope Map
View variants at this location
Epitope GQMVHQAI   Epitope Alignment
Variants
GQMVHQsI   HLA association; escape documented in this paper
GQMVHQAl   HLA association; escape documented in this paper
Epitope Name GI8
Species (MHC/HLA human(B*1302)

Variant Details

Showing all: 2 variant(s).


Variant ID.  3748
Epitope Seq.  GQMVHQAI
Variant Seq.  GQMVHQsI
Mutations A/S
Epitope Location A7S
HXB2 Location A146S
Mutation Type A: HLA association
E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Relative replication capacity assay
Note Mutation A146S in epitope GQMVHQAI, i.e. GQMVHQsI, is associated with HLA-B*13/1302.


Variant ID.  3749
Epitope Seq.  GQMVHQAI
Variant Seq.  GQMVHQAl
Mutations I/L
Epitope Location I8L
HXB2 Location I147L
Mutation Type A: HLA association
E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Relative replication capacity assay
Note Mutation I147L in epitope GQMVHQAI, i.e. GQMVHQAl, is associated with HLA-B*13/1302.

References

Shahid2015 Aniqa Shahid, Alex Olvera, Gursev Anmole, Xiaomei T. Kuang, Laura A. Cotton, Montserrat Plana, Christian Brander, Mark A. Brockman, and Zabrina L. Brumme. Consequences of HLA-B*13-Associated Escape Mutations on HIV-1 Replication and Nef Function. J. Virol., 89(22):11557-11571, Nov 2015. PubMed ID: 26355081. Show all entries for this paper.


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