HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 61159

HXB2 Location  Pol(132-140)   Pol Epitope Map
View variants at this location
Epitope LIGPTPVNI   Epitope Alignment
Species (MHC/HLA human, mouse

Variant Details

Showing all: 1 variant(s).

Variant ID.  3596
Epitope Seq.  LIGPTPVNI
Variant Seq.  LvGPTPVNI
Mutations I/V
Epitope Location I2V
HXB2 Location I133V
Mutation Type
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Other
Note Epitope variant LvGPTPVNI has a stronger response than the epitope LIGPTPVNI. It is present in mosaic 1 of the second generation vaccine, tHIVconsvX.


Ondondo2016 Beatrice Ondondo, Hayato Murakoshi, Genevieve Clutton, Sultan Abdul-Jawad, Edmund G.-T. Wee, Hiroyuki Gatanaga, Shinichi Oka, Andrew J. McMichael, Masafumi Takiguchi, Bette Korber, and Tomáš Hanke. Novel Conserved-region T-cell Mosaic Vaccine With High Global HIV-1 Coverage Is Recognized by Protective Responses in Untreated Infection. Mol. Ther., 24(4):832-842, Apr 2016. PubMed ID: 26743582. Show all entries for this paper.

Questions or comments? Contact us at
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health