HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(263-272) | Gag Epitope Map
View variants at this location |
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| Epitope |
KRWIILGLNK
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Epitope Alignment | |||||||||||||||||||
| Variants |
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| Epitope Name | B27-KK10 | ||||||||||||||||||||
| Species (MHC/HLA) | human | ||||||||||||||||||||
Showing all: 6 variant(s).
| Variant ID. | 3516 |
|---|---|
| Epitope Seq. | KRWIILGLNK |
| Variant Seq. | eRWIILGLNK |
| Mutations | K/E |
| Epitope Location | K1E |
| HXB2 Location | K131E |
| Mutation Type | A: HLA association TCR: TCR related mutation |
| Method | Other, Tetramer binding |
| Note | At t1, subject 2 (ACS 19885) carried 3.2% eRWIILGLNK. |
| Variant ID. | 3517 |
|---|---|
| Epitope Seq. | KRWIILGLNK |
| Variant Seq. | rRWIILGLNK |
| Mutations | K/R |
| Epitope Location | K1R |
| HXB2 Location | K131R |
| Mutation Type | A: HLA association TCR: TCR related mutation |
| Method | Other, Tetramer binding |
| Note | At t2, subject 7 (ACS 18839) carried 5.3% rRWIILGLNK. |
| Variant ID. | 3518 |
|---|---|
| Epitope Seq. | KRWIILGLNK |
| Variant Seq. | KRWIIpGLNK |
| Mutations | L/P |
| Epitope Location | L6P |
| HXB2 Location | L136P |
| Mutation Type | A: HLA association TCR: TCR related mutation |
| Method | Other, Tetramer binding |
| Note | At t1, subject 2 (ACS 19885) carried 3.2% KRWIIpGLNK. |
| Variant ID. | 3519 |
|---|---|
| Epitope Seq. | KRWIILGLNK |
| Variant Seq. | KRWIImGLNK |
| Mutations | L/M |
| Epitope Location | L6M |
| HXB2 Location | L136M |
| Mutation Type | A: HLA association TCR: TCR related mutation |
| Method | Other, Tetramer binding |
| Note | At t1, subject 6 (ACS 18840) carried 68% KRWIImGLNK. Subject 7 (ACS 18839) carried 100% of this variant at t1 and 42.1% at t2. |
| Variant ID. | 3520 |
|---|---|
| Epitope Seq. | KRWIILGLNK |
| Variant Seq. | KRWIvmGLNK |
| Mutations | I/V L/M |
| Epitope Location | I5V L6M |
| HXB2 Location | I135V L136M |
| Mutation Type | A: HLA association TCR: TCR related mutation |
| Method | Other, Tetramer binding |
| Note | At t2, subject 2 (ACS 19885) carried 14.3% KRWIvmGLNK. |
| Variant ID. | 3521 |
|---|---|
| Epitope Seq. | KRWIILGLNK |
| Variant Seq. | KRWIIiGLNK |
| Mutations | L/M |
| Epitope Location | L6M |
| HXB2 Location | L136M |
| Mutation Type | A: HLA association TCR: TCR related mutation |
| Method | Other, Tetramer binding |
| Note | At t1, subject 6 (ACS 18840) carried 4% KRWIIiGLNK. |
Costa2015 Ana I. Costa, Dan Koning, Kristin Ladell, James E. McLaren, Bart P. X. Grady, Ingrid M. M. Schellens, Petra van Ham, Monique Nijhuis, José A. M. Borghans, Can Keşmir, David A. Price, and Debbie van Baarle. Complex T-Cell Receptor Repertoire Dynamics Underlie the CD8+ T-Cell Response to HIV-1. J. Virol., 89(1):110-119, Jan 2015. PubMed ID: 25320304. Show all entries for this paper.