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Found 1 matching record:

Displaying record number 60508

HXB2 Location  Gag(263-272)   Gag Epitope Map
View variants at this location
Epitope KRWIILGLNK   Epitope Alignment
Variants
eRWIILGLNK   HLA association; TCR related mutation
rRWIILGLNK   HLA association; TCR related mutation
KRWIIpGLNK   HLA association; TCR related mutation
KRWIImGLNK   HLA association; TCR related mutation
KRWIvmGLNK   HLA association; TCR related mutation
KRWIIiGLNK   HLA association; TCR related mutation
Epitope Name B27-KK10
Species (MHC/HLA human

Variant Details

Showing all: 6 variant(s).


Variant ID.  3516
Epitope Seq.  KRWIILGLNK
Variant Seq.  eRWIILGLNK
Mutations K/E
Epitope Location K1E
HXB2 Location K131E
Mutation Type A: HLA association
TCR: TCR related mutation
Method Other, Tetramer binding
Note At t1, subject 2 (ACS 19885) carried 3.2% eRWIILGLNK.


Variant ID.  3517
Epitope Seq.  KRWIILGLNK
Variant Seq.  rRWIILGLNK
Mutations K/R
Epitope Location K1R
HXB2 Location K131R
Mutation Type A: HLA association
TCR: TCR related mutation
Method Other, Tetramer binding
Note At t2, subject 7 (ACS 18839) carried 5.3% rRWIILGLNK.


Variant ID.  3518
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIIpGLNK
Mutations L/P
Epitope Location L6P
HXB2 Location L136P
Mutation Type A: HLA association
TCR: TCR related mutation
Method Other, Tetramer binding
Note At t1, subject 2 (ACS 19885) carried 3.2% KRWIIpGLNK.


Variant ID.  3519
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIImGLNK
Mutations L/M
Epitope Location L6M
HXB2 Location L136M
Mutation Type A: HLA association
TCR: TCR related mutation
Method Other, Tetramer binding
Note At t1, subject 6 (ACS 18840) carried 68% KRWIImGLNK. Subject 7 (ACS 18839) carried 100% of this variant at t1 and 42.1% at t2.


Variant ID.  3520
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIvmGLNK
Mutations I/V L/M
Epitope Location I5V L6M
HXB2 Location I135V L136M
Mutation Type A: HLA association
TCR: TCR related mutation
Method Other, Tetramer binding
Note At t2, subject 2 (ACS 19885) carried 14.3% KRWIvmGLNK.


Variant ID.  3521
Epitope Seq.  KRWIILGLNK
Variant Seq.  KRWIIiGLNK
Mutations L/M
Epitope Location L6M
HXB2 Location L136M
Mutation Type A: HLA association
TCR: TCR related mutation
Method Other, Tetramer binding
Note At t1, subject 6 (ACS 18840) carried 4% KRWIIiGLNK.

References

Costa2015 Ana I. Costa, Dan Koning, Kristin Ladell, James E. McLaren, Bart P. X. Grady, Ingrid M. M. Schellens, Petra van Ham, Monique Nijhuis, José A. M. Borghans, Can Keşmir, David A. Price, and Debbie van Baarle. Complex T-Cell Receptor Repertoire Dynamics Underlie the CD8+ T-Cell Response to HIV-1. J. Virol., 89(1):110-119, Jan 2015. PubMed ID: 25320304. Show all entries for this paper.


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