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Found 1 matching record:

Displaying record number 59439

HXB2 Location  Vif(48-57)   Vif Epitope Map
View variants at this location
Epitope HPKVSSEVHI   Epitope Alignment
Variants
nPKVSSEVHI   escape documented in this paper; observed variant
Epitope Name Vif-HI10
Species (MHC/HLA human(B*42:01)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3498
Epitope Seq.  HPKVSSEVHI
Variant Seq.  nPKVSSEVHI
Mutations H/N
Epitope Location H1N
HXB2 Location H34N
Mutation Type E: escape documented in this paper
OV: observed variant
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Other, Tetramer binding
Note 32% of B*4201+ and 9% of B*4201- subjects (n=1857) carried this escape variant, nPKVSSEVHI.

References

Kloverpris2015 Henrik N Kløverpris, Reuben McGregor, James E. McLaren, Kristin Ladell, Mikkel Harndahl, Anette Stryhn, Jonathan M. Carlson, Catherine Koofhethile, Bram Gerritsen, Can Keşmir, Fabian Chen, Lynn Riddell, Graz Luzzi, Alasdair Leslie, Bruce D. Walker, Thumbi Ndung'u, Søren Buus, David A. Price, and Philip J. Goulder. CD8+ TCR Bias and Immunodominance in HIV-1 Infection. J. Immunol., 194(11):5329-5345, 1 Jun 2015. PubMed ID: 25911754. Show all entries for this paper.


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