HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(22-30) | Gag Epitope Map
View variants at this location |
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| Epitope |
RPGGKKHYM
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Epitope Alignment | ||||||||||||||||
| Variants |
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| Epitope Name | Gag-RM9 | |||||||||||||||||
| Species (MHC/HLA) | human(B*42:01) | |||||||||||||||||
Showing all: 5 variant(s).
| Variant ID. | 3477 |
|---|---|
| Epitope Seq. | {IRL}RPGGKKHYM |
| Variant Seq. | {IsL}RPGGKKHYM |
| Mutations | R/S |
| Epitope Location | R-2S |
| HXB2 Location | R20S |
| Mutation Type | E: escape documented in this paper OV: observed variant |
| Epitope Subtype | C |
| Variant Subtype | C |
| Method | Other, Tetramer binding |
| Note | 5% of B*4201+ and 2% of B*4201- subjects (n=1767) carried this upstream escape variant, {IsL}RPGGKKHYM. |
| Variant ID. | 3478 |
|---|---|
| Epitope Seq. | RPGGKKHYM |
| Variant Seq. | RPGGKKqYM |
| Mutations | H/Q |
| Epitope Location | H7Q |
| HXB2 Location | H28Q |
| Mutation Type | DR: diminished response E: escape documented in this paper OV: observed variant |
| Epitope Subtype | C |
| Variant Subtype | C |
| Method | Other, Tetramer binding |
| Note | 29% of B*4201+ and 13% of B*4201- subjects (n=1765) carried this escape variant, RPGGKKqYM. |
| Variant ID. | 3479 |
|---|---|
| Epitope Seq. | RPGGKKHYM |
| Variant Seq. | RPGGKKsYM |
| Mutations | H/S |
| Epitope Location | H7S |
| HXB2 Location | H28S |
| Mutation Type | DR: diminished response E: escape documented in this paper OV: observed variant |
| Epitope Subtype | C |
| Variant Subtype | C |
| Method | Other, Tetramer binding |
| Note | 6% of B*4201+ and 2% of B*4201- subjects (n=1765) carried this escape variant, RPGGKKsYM. |
| Variant ID. | 3480 |
|---|---|
| Epitope Seq. | RPGGKKHYM |
| Variant Seq. | RPGGKKrYM |
| Mutations | H/R |
| Epitope Location | H7R |
| HXB2 Location | H28R |
| Mutation Type | DR: diminished response E: escape documented in this paper OV: observed variant |
| Epitope Subtype | C |
| Variant Subtype | C |
| Method | Other, Tetramer binding |
| Note | 22% of B*4201+ and 13% of B*4201- subjects (n=1765) carried this escape variant, RPGGKKrYM. |
| Variant ID. | 3481 |
|---|---|
| Epitope Seq. | RPGGKKHYM |
| Variant Seq. | RPGGKKHYk |
| Mutations | M/K |
| Epitope Location | M9K |
| HXB2 Location | M30K |
| Mutation Type | DR: diminished response E: escape documented in this paper OV: observed variant |
| Epitope Subtype | C |
| Variant Subtype | C |
| Method | Other, Tetramer binding |
| Note | 14% of B*4201+ and 7% of B*4201- subjects (n=1765) carried this escape variant, RPGGKKHYk. |
Kloverpris2015 Henrik N Kløverpris, Reuben McGregor, James E. McLaren, Kristin Ladell, Mikkel Harndahl, Anette Stryhn, Jonathan M. Carlson, Catherine Koofhethile, Bram Gerritsen, Can Keşmir, Fabian Chen, Lynn Riddell, Graz Luzzi, Alasdair Leslie, Bruce D. Walker, Thumbi Ndung'u, Søren Buus, David A. Price, and Philip J. Goulder. CD8+ TCR Bias and Immunodominance in HIV-1 Infection. J. Immunol., 194(11):5329-5345, 1 Jun 2015. PubMed ID: 25911754. Show all entries for this paper.