HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 59228

HXB2 Location  Nef(71-81)   Nef Epitope Map
View variants at this location
Epitope RPQVPLRPMTY   Epitope Alignment
RPQVPLRaMTY   HLA association
Epitope Name RY11
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).

Variant ID.  3367
Variant Seq.  RPQVPLRaMTY
Mutations P/A
Epitope Location P8A
HXB2 Location P78A
Mutation Type A: HLA association
Epitope Subtype B
Variant Subtype B
Method HLA binding, Other, Structural prediction
Note Complex of B*3501 with variant P8A of RY11, RPQVPLRaMTY, is more stable than B*3501-RY11, but specificity to the cognate TCR is maintained.


Yanaka2014 Saeko Yanaka, Takamasa Ueno, Yi Shi, Jianxun Qi, George F. Gao, Kouhei Tsumoto, and Kenji Sugase. Peptide-Dependent Conformational Fluctuation Determines the Stability of the Human Leukocyte Antigen Class I Complex. J. Biol. Chem., 289(35):24680-24690, 29 Aug 2014. PubMed ID: 25028510. Show all entries for this paper.

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