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Found 1 matching record:

Displaying record number 59055

HXB2 Location  Tat(38-47)   Tat Epitope Map
View variants at this location
Epitope FQKKGLGISY   Epitope Alignment
Variants
FQtKGLGISY   diminished response; escape documented in this paper
Epitope Name Tat 38-47
Species (MHC/HLA human(B*15:03)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3227
Epitope Seq.  FQKKGLGISY
Variant Seq.  FQtKGLGISY
Mutations K/T
Epitope Location K3T
HXB2 Location K40T
Mutation Type DR: diminished response
E: escape documented in this paper
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note Calculated time to escape to FQtKGLGISY was 105 days.

References

Liu2013a Michael K. P. Liu, Natalie Hawkins, Adam J. Ritchie, Vitaly V. Ganusov, Victoria Whale, Simon Brackenridge, Hui Li, Jeffrey W. Pavlicek, Fangping Cai, Melissa Rose-Abrahams, Florette Treurnicht, Peter Hraber, Catherine Riou, Clive Gray, Guido Ferrari, Rachel Tanner, Li-Hua Ping, Jeffrey A. Anderson, Ronald Swanstrom, CHAVI Core B, Myron Cohen, Salim S. Abdool Karim, Barton Haynes, Persephone Borrow, Alan S. Perelson, George M. Shaw, Beatrice H. Hahn, Carolyn Williamson, Bette T. Korber, Feng Gao, Steve Self, Andrew McMichael, and Nilu Goonetilleke. Vertical T Cell Immunodominance and Epitope Entropy Determine HIV-1 Escape. J. Clin. Invest., 123(1):380-393, 2 Jan 2013. PubMed ID: 23221345. Show all entries for this paper.


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