HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 59035

HXB2 Location  Vpr(48-57)   Vpr Epitope Map
View variants at this location
Epitope ETYGDTWTGV   Epitope Alignment
dTYGDTWTGV   observed variant
Epitope Name Vpr-EV10
Species (MHC/HLA human(A*68:02)

Variant Details

Showing all: 1 variant(s).

Variant ID.  3217
Epitope Seq.  ETYGDTWTGV
Variant Seq.  dTYGDTWTGV
Mutations E/D
Epitope Location E1D
HXB2 Location E48D
Mutation Type OV: observed variant
Epitope Subtype C
Variant Subtype C
Method Sequence
Note The E48D variant of Vpr EV10, dTYGDTWTGV was observed in 53% of A*6802+ subjects as compared to 16% of A*6802- subjects.


Kloverpris2013c Henrik N. Kløverpris, Anette Stryhn, Mikkel Harndahl, Jonathan M. Carlson, Alasdair J. Leslie, Fabian Chen, Lynn Riddell, Joseph Mulenga, Bruce D. Walker, Thumbi Ndung'u, Søren Buus, and Philip Goulder. HLA-A*68:02-Restricted Gag-Specific Cytotoxic T Lymphocyte Responses Can Drive Selection Pressure on HIV but Are Subdominant and Ineffective. AIDS, 27(11):1717-1723, 17 Jul 2013. PubMed ID: 23525031. Show all entries for this paper.

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