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HIV Molecular Immunology Database

Search the Epitope Variant and Escape Mutation Database

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Found 1 matching record:

Displaying record number 59034

HXB2 Location  Pol(593-600)   Pol Epitope Map
View variants at this location
Epitope ETFYVDGA   Epitope Alignment
Variants
{v}ETFYVDGA   observed variant
ETFYVDGA{S}   observed variant
ETFYVDGA{ANRETKk}   observed variant
Epitope Name Pol-EA8 RT
Species (MHC/HLA human(A*68:02)

Variant Details

Showing all: 3 variant(s).


Variant ID.  3214
Epitope Seq.  {A}ETFYVDGA
Variant Seq.  {v}ETFYVDGA
Mutations A/V
Epitope Location A-1V
HXB2 Location A592V
Mutation Type OV: observed variant
Epitope Subtype C
Variant Subtype C
Method Sequence
Note The A592V variant of Pol EA8, {v}ETFYVDGA is a flanking region mutation.


Variant ID.  3215
Epitope Seq.  ETFYVDGA{A}
Variant Seq.  ETFYVDGA{S}
Mutations A/S
Epitope Location A+1S
HXB2 Location A601S
Mutation Type OV: observed variant
Epitope Subtype C
Variant Subtype C
Method Sequence
Note The A601S variant of Pol EA8, ETFYVDGA{S} is a flanking region mutation.


Variant ID.  3216
Epitope Seq.  ETFYVDGA{ANRETKI}
Variant Seq.  ETFYVDGA{ANRETKk}
Mutations I/K
Epitope Location I+7K
HXB2 Location I607K
Mutation Type OV: observed variant
Epitope Subtype C
Variant Subtype C
Method Sequence
Note The I607K variant of Pol EA8, ETFYVDGA{ANRETKk} is a flanking region mutation.

References

Kloverpris2013c Henrik N. Kløverpris, Anette Stryhn, Mikkel Harndahl, Jonathan M. Carlson, Alasdair J. Leslie, Fabian Chen, Lynn Riddell, Joseph Mulenga, Bruce D. Walker, Thumbi Ndung'u, Søren Buus, and Philip Goulder. HLA-A*68:02-Restricted Gag-Specific Cytotoxic T Lymphocyte Responses Can Drive Selection Pressure on HIV but Are Subdominant and Ineffective. AIDS, 27(11):1717-1723, 17 Jul 2013. PubMed ID: 23525031. Show all entries for this paper.


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