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Found 1 matching record:

Displaying record number 58745

HXB2 Location  Gag(308-316)   Gag Epitope Map
View variants at this location
Epitope QASQEVKNW   Epitope Alignment
Variants
QASQdVKNW   non-susceptible form
Species (MHC/HLA human(B*57)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3134
Epitope Seq.  QASQEVKNW
Variant Seq.  QASQdVKNW
Mutations E/D
Epitope Location E5D
HXB2 Location E312D
Mutation Type NSF: non-susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Variant QASQdVKNW is seen in both ES38 and CP2 HIV-1 sequences even though CP2 does not carry HLA-B*57 allele. Neither subject can recognize this variant.

References

Buckheit2012 Robert W. Buckheit, III, Tracy G. Allen, Angela Alme, Maria Salgado, Karen A. O'Connell, Sarah Huculak, Oluwaseun Falade-Nwulia, Thomas M. Williams, Joel E. Gallant, Robert F. Siliciano, and Joel N. Blankson. Host Factors Dictate Control of Viral Replication in Two HIV-1 Controller/Chronic Progressor Transmission Pairs. Nat Commun, 3:716, 2012. PubMed ID: 22395607. Show all entries for this paper.


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