HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(277-285) | Gag Epitope Map
View variants at this location |
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|---|---|---|---|---|---|---|
| Epitope |
YSPTSILDI
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Epitope Alignment | ||||
| Variants |
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| Species (MHC/HLA) | human(C*12) | |||||
Showing all: 1 variant(s).
| Variant ID. | 3109 |
|---|---|
| Epitope Seq. | YSPTSILDI |
| Variant Seq. | YSPvSILDI |
| Mutations | T/V |
| Epitope Location | T4V |
| HXB2 Location | T280V |
| Mutation Type | E: escape documented in this paper |
| Epitope Subtype | B |
| Variant Subtype | B |
| Method | CD8 T-cell Elispot - IFNy |
| Note | C-mut YSPvSILDI that is a variant of Gag YSPTSILDI is restricted by HLA-Cw*12. It is shown to be an escape by EliSpot. |
Blais2012 Marie-Eve Blais, Yonghong Zhang, Tim Rostron, Harry Griffin, Stephen Taylor, Keyi Xu, Huiping Yan, Hao Wu, Ian James, Mina John, Tao Dong, and Sarah L. Rowland-Jones. High Frequency of HIV Mutations Associated with HLA-C Suggests Enhanced HLA-C-Restricted CTL Selective Pressure Associated with an AIDS-Protective Polymorphism. J. Immunol., 188(9):4663-4670, 1 May 2012. PubMed ID: 22474021. Show all entries for this paper.