HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 58695

HXB2 Location  Pol(464-473)   Pol Epitope Map
View variants at this location
Epitope ILKEPVHGVY   Epitope Alignment
ILrEPVHGVY   escape documented in this paper
Species (MHC/HLA human(C*03:03)

Variant Details

Showing all: 1 variant(s).

Variant ID.  3108
Epitope Seq.  ILKEPVHGVY
Variant Seq.  ILrEPVHGVY
Mutations K/R
Epitope Location K3R
HXB2 Location K466R
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy
Note C-mut ILrEPVHGVY that is a variant of Pol ILKEPVHGVY is restricted by HLA-Cw*0302.


Blais2012 Marie-Eve Blais, Yonghong Zhang, Tim Rostron, Harry Griffin, Stephen Taylor, Keyi Xu, Huiping Yan, Hao Wu, Ian James, Mina John, Tao Dong, and Sarah L. Rowland-Jones. High Frequency of HIV Mutations Associated with HLA-C Suggests Enhanced HLA-C-Restricted CTL Selective Pressure Associated with an AIDS-Protective Polymorphism. J. Immunol., 188(9):4663-4670, 1 May 2012. PubMed ID: 22474021. Show all entries for this paper.

Questions or comments? Contact us at
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health