HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Nef(73-82) | Nef Epitope Map
View variants at this location |
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| Epitope |
QVPLRPMTYK
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Epitope Alignment | |||||||
| Variants |
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| Species (MHC/HLA) | human(A*03:01) | ||||||||
Showing all: 2 variant(s).
| Variant ID. | 2837 |
|---|---|
| Epitope Seq. | QVPLRPMTYK{AA} |
| Variant Seq. | QVPLRPMTYK{gA} |
| Mutations | A/G |
| Epitope Location | A+1G |
| HXB2 Location | A83G |
| Mutation Type | IE: inferred escape |
| Epitope Subtype | B |
| Variant Subtype | B |
| Method | Sequence |
| Note | 8/14 sequences of peptide QVPLRPMTYK{AA} varied at 639 DFOSx to QVPLRPMTYK{gA}. Position 83 in the peptide is marked as being under selection to vary. |
| Variant ID. | 2839 |
|---|---|
| Epitope Seq. | QVPLRPMTYK{AA} |
| Variant Seq. | QVPLRPMTfK{gA} |
| Mutations | A/G Y/F |
| Epitope Location | A+1G Y9F |
| HXB2 Location | A83G Y81F |
| Mutation Type | IE: inferred escape |
| Epitope Subtype | B |
| Variant Subtype | B |
| Method | Sequence |
| Note | 5/14 and 12/13 sequences of peptide QVPLRPMTYK{AA} varied at 639 and 821 DFOSx to QVPLRPMTfK{gA}. Positions 81 and 83 in the peptide are marked as being under selection to vary. |
Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.