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Found 1 matching record:

Displaying record number 58242

HXB2 Location  Nef(73-82)   Nef Epitope Map
View variants at this location
Epitope QVPLRPMTYK   Epitope Alignment
Variants
QVPLRPMTYK{gA}   inferred escape
QVPLRPMTfK{gA}   inferred escape
Species (MHC/HLA human(A*0301)

Variant Details

Showing all: 2 variant(s).


Variant ID.  2837
Epitope Seq.  QVPLRPMTYK{AA}
Variant Seq.  QVPLRPMTYK{gA}
Mutations A/G
Epitope Location A+1G
HXB2 Location A83G
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 8/14 sequences of peptide QVPLRPMTYK{AA} varied at 639 DFOSx to QVPLRPMTYK{gA}. Position 83 in the peptide is marked as being under selection to vary.


Variant ID.  2839
Epitope Seq.  QVPLRPMTYK{AA}
Variant Seq.  QVPLRPMTfK{gA}
Mutations A/G Y/F
Epitope Location A+1G Y9F
HXB2 Location A83G Y81F
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 5/14 and 12/13 sequences of peptide QVPLRPMTYK{AA} varied at 639 and 821 DFOSx to QVPLRPMTfK{gA}. Positions 81 and 83 in the peptide are marked as being under selection to vary.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


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