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Found 1 matching record:

Displaying record number 58238

HXB2 Location  gp160(352-361)   gp160 Epitope Map
View variants at this location
Epitope QFRNKTIVF   Epitope Alignment
Variants
QFkNKTIVF   inferred escape
QFRNKaIVF   observed variant
QFnNKTIVF   inferred escape
Species (MHC/HLA human(C*04:01)

Variant Details

Showing all: 3 variant(s).


Variant ID.  2813
Epitope Seq.  QFRNKTIVF
Variant Seq.  QFkNKTIVF
Mutations R/K
Epitope Location R3K
HXB2 Location R354K
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 11/15, 12/12, 4/5, 10/12 and 3/5 sequences of epitope QFRNKTIVF varied at 14, 32, 102, 159 and 592 DFOSx to QFkNKTIVF. Position 354 in the epitope is marked as being under selection to vary.


Variant ID.  2815
Epitope Seq.  QFRNKTIVF
Variant Seq.  QFRNKaIVF
Mutations T/A
Epitope Location T6A
HXB2 Location T357A
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/15 sequences of epitope QFRNKTIVF varied at 14 DFOSx to QFRNKaIVF.


Variant ID.  2817
Epitope Seq.  QFRNKTIVF
Variant Seq.  QFnNKTIVF
Mutations R/N
Epitope Location R3N
HXB2 Location R354N
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/5 and 2/12 sequences of epitope QFRNKTIVF varied at 102 and 159 DFOSx to QFnNKTIVF.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


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