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Displaying record number 58238

HXB2 Location gp160(352-361) gp160 Epitope Map
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QFRNKTIVF

`QFkNKTIVF`		inferred escape
`QFRNKaIVF`		observed variant
`QFnNKTIVF`		inferred escape

Species (MHC/HLA) human(C*04:01)

Variant Details

Showing all: 3 variant(s).

Variant ID.	`2813`
Epitope Seq.	`QFRNKTIVF`
Variant Seq.	`QFkNKTIVF`
Mutations	R/K
Epitope Location	R3K
HXB2 Location	R354K
Mutation Type	IE: inferred escape
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	11/15, 12/12, 4/5, 10/12 and 3/5 sequences of epitope QFRNKTIVF varied at 14, 32, 102, 159 and 592 DFOSx to QFkNKTIVF. Position 354 in the epitope is marked as being under selection to vary.

Variant ID.	`2815`
Epitope Seq.	`QFRNKTIVF`
Variant Seq.	`QFRNKaIVF`
Mutations	T/A
Epitope Location	T6A
HXB2 Location	T357A
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	1/15 sequences of epitope QFRNKTIVF varied at 14 DFOSx to QFRNKaIVF.

Variant ID.	`2817`
Epitope Seq.	`QFRNKTIVF`
Variant Seq.	`QFnNKTIVF`
Mutations	R/N
Epitope Location	R3N
HXB2 Location	R354N
Mutation Type	IE: inferred escape
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	1/5 and 2/12 sequences of epitope QFRNKTIVF varied at 102 and 159 DFOSx to QFnNKTIVF.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.