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Found 1 matching record:

Displaying record number 58227

HXB2 Location  Vif(119-127)   Vif Epitope Map
View variants at this location
Epitope AIRKAILGR   Epitope Alignment
Variants
AIRtAILGR   inferred escape
AIReAILGR   inferred escape
Species (MHC/HLA human(A*31:01)

Variant Details

Showing all: 2 variant(s).


Variant ID.  2790
Epitope Seq.  AIRKAILGR
Variant Seq.  AIRtAILGR
Mutations K/T
Epitope Location K4T
HXB2 Location K122T
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 4/7 sequences of epitope AIRKAlLGR varied at 181 DFOSx to AIRtAlLGR. Position 122 is marked as being selected to vary.


Variant ID.  2791
Epitope Seq.  AIRKAILGR
Variant Seq.  AIReAILGR
Mutations K/E
Epitope Location K4E
HXB2 Location K122E
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 9/12 sequences of epitope AIRKAlLGR varied at 412 DFOSx to AIReAlLGR. Position 122 is marked as being selected to vary.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


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