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Displaying record number 58152

HXB2 Location  gp160(217-226)   gp160 Epitope Map
View variants at this location
Epitope YCAPAGFAIL   Epitope Alignment
Variants
YCAPAGFAIi   escape documented in this paper
Epitope Name YL10
Species (MHC/HLA human(C*01:02)

Variant Details

Showing all: 1 variant(s).


Variant ID.  2742
Epitope Seq.  YCAPAGFAIL
Variant Seq.  YCAPAGFAIi
Mutations L/I
Epitope Location L10I
HXB2 Location L226I
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Longitudinal study
Note Variant YCAPAGFAIi had replaced the wild type sequence by 400 days post-infection. Sequence change was associated with loss of EliSpot response to the epitope.

References

Liu2011a Yi Liu, John P. McNevin, Sarah Holte, M. Juliana McElrath, and James I. Mullins. Dynamics of Viral Evolution and CTL Responses in HIV-1 Infection. PLoS One, 6(1):e15639, 2011. PubMed ID: 21283794. Show all entries for this paper.


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